Diabetes mellitus (DM) is a worldwide disease characterized by metabolic disturbances, frequently associated with high risk of atherosclerosis and renal and nervous system damage. Here, we assessed whether metabolites reflecting oxidative redox state, arginine and nitric oxide metabolism, are differentially distributed between serum and red blood cells (RBC), and whether significant metabolism ...

Accepted 6 November 1995 Abstract Group B ,-haemolytic Streptococcus (GBS) may cause severe septic shock and death in neonates, whereas this is rarely the case in adults. As impaired red blood cell (RBC) deformability might disturb microcirculation in septic shock, the in vitro effects of GBS (1-7X108 cfu/ml) on RBC deformation (rheoscope) and haemolysis were studied in blood from preterm infan...

A modified antiglobulin test, based on the high affinity between the Fc portion of the red blood cell (RBC) bound IgG and the Fc receptor on the myeloid cell K-562, was utilized for demonstration of immunoglobulins (Ig) on thalassemic RBC. Ig was found on the RBC of 73 out of 80 patients with thalassemia. The immunoglobulins on the thalassemic RBC belonged to the IgG subclass and were autoreact...

BACKGROUND Helicobacter pylori eradication rates have tended to decrease recently possibly related with increasing antibiotic resistance. The present study investigated the efficacy of three different ranitidine bismuth citrate (RBC) based triple regimens in a population with high prevalence of H. pylori. METHODS 300 consecutive H. pylori positive patients with non-ulcer dyspepsia were random...

VVhen native and acid-denatured Jactate dehydregenase (LDH) were incubated with total lysosomal enzymes in vitro, amino acids from their degradation were produced at various acidic pH. The pH profile in the overall degradation of natiye LDH was markedly different from that of acid-denatured LDH. Disappearance of the 35-kDa subunit of native LDH was markedly suppressed by a low level of cystatin...

Improved healing rates are obtained upon the application of composite dressings as compared to pure BC. mBC-SS2 prevents excessive wound contraction which leads hypertrophied neo-tissue formation when rBC-SS2 is used. The collagen fibers aligned along width microgroove mBC and its composites while anarchic deposited in presence rBC composites. Relatively rBC-SS2, constitutes an improved dressin...

Rational selection of predicted peptides to be employed as templates in molecular imprinting was carried out for the heat-denatured non-structural protein 1 (NS1) dengue virus (DENV). Conservation analysis among 301 sequences Brazilian isolates DENV and zika (ZIKV) NS1 by UniProtKB, peptide based on silico data conservational, structural immunogenic properties sequences. The selected (from NS1)...