Recently, the Vaccines to Vaccinate (v2V) initiative was reconfigured into the Partnership for Dengue Control (PDC), a multi-sponsored and independent initiative. This redirection is consistent with the growing consensus among the dengue-prevention community that no single intervention will be sufficient to control dengue disease. The PDC's expectation is that when an effective dengue virus (DE...

Dengue is generally believed to be one of the most hazardous vector-borne diseases, with over 40% of the world’s population at risk of an infection [1]. While in the past the disease has mainly been observed in the tropical regions, recent studies suggest that, under the pressure of future climate change, new areas as far north as Europe may become endangered. In fact, in 2010 the first Europea...

Dengue viruses have spread rapidly within countries and across regions in the past few decades, resulting in an increased frequency of epidemics and severe dengue disease, hyperendemicity of multiple dengue virus serotypes in many tropical countries, and autochthonous transmission in Europe and the USA. Today, dengue is regarded as the most prevalent and rapidly spreading mosquito-borne viral d...

We examined variations in dengue vector control costs and resource consumption between the District Health Departments (DHDs) and Local Authorities (LAs) to assist informed decision making as to the future roles of these agencies in the delivery of dengue vector control services in Malaysia. Data were collected from the vector control units of DHDs and LAs in 8 selected districts. We captured c...

Dengue infection is the most important arbo-virus infection of humans and the most important tropical infectious disease after malaria. This disease is characterized by headache, arthralgia, myalgia, rash, nausea, vomiting. Four serotypes of DENV exist, and severe illness is usually associated with secondary infection by a different serotype. Aedes aegypti is the vector for transmission of this...

An outbreak of dengue-like syndrome occurred in Toamasina from January through March 2006. Dengue type l or chikungunya viruses were detected in 38 of 55 patients sampled. Aedes albopictus was the only potential vector collected. Of 4,242 randomly selected representative residents interviewed retrospectively, 67.5% reported a dengue-like syndrome during this period.

BACKGROUND Several factors, including environmental and climatic factors, influence the transmission of vector-borne diseases. Nevertheless, the identification and relative importance of climatic factors for vector-borne diseases remain controversial. Dengue is the world's most important viral vector-borne disease, and the controversy about climatic effects also applies in this case. Here we ad...

Dengue is a viral disease transmitted by the Aedes aegypti mosquito vector, and is caused by four antigenically related flaviviruses (dengue virus serotypes one through four (DENV-1-4)). Dengue is endemic throughout large parts of the Americas and Asia, and is increasingly reported in Africa. More than 2.5 billion people are at high risk of infection in more than 100 endemic countries throughou...

BACKGROUND Dengue fever is the most common and widespread mosquito-borne arboviral disease in the world. There is a compelling need for cost-effective approaches and practical tools that can reliably measure real-time dengue transmission dynamics that enable more accurate and useful predictions of incidence and outbreaks. Sensitive surveillance tools do not exist today, and only a small handful...