We characterized and imaged dental calculus using swept-source optical coherence tomography (SS-OCT). The refractive indices of enamel, dentin, cementum, and calculus were measured as 1.625 ± 0.024, 1.534 ± 0.029, 1.570 ± 0.021, and 2.097 ± 0.094, respectively. Dental calculus leads strong scattering properties, and thus, the region can be identified from enamel with SS-OCT imaging. An extracte...

In the developing tooth, 1-hydroxyethylidene-1,1-bisphosphonate (HEBP) causes hypoplasia and hypomineralization of enamel and dentine. The present study was undertaken to clarify the effects of HEBP on the formation of dental tissues of tooth germs in an organ culture system. Mandibular first molars from 17.5-day-old mouse embryos were cultured with or without 250 microM HEBP in culture medium....

Periodontitis is primarily a dental plaque induced inflammatory disease. Anatomic factors such as cervical enamel projections, enamel pearls, and developmental grooves are often associated with advanced, localized periodontal destruction. Enamel projections and pearls are mostly associated with molars. Enamel projections in the furcation areas of molars have no true attachment and are therefore...

Dihydropyrimidinase-related protein 4 (Dpysl4) is a known regulator of hippocampal neuron development. Here, we report that Dpysl4 is involved in growth regulation, polarization and differentiation of dental epithelial cells during tooth germ morphogenesis. A reduction in Dpysl4 gene expression in the tooth germ produced a loss of ameloblasts, resulting in the decrease of synthesis and secretio...

Applications of Cu-HyBrID laser (copper laser with Hydrogen Bromide In Discharge) in Dentistry and AFM (atomic force microscopy) evaluations of dental tissues irradiated by laser are seldom reported in the literature. This work presents an AFM investigation of the cross-section of a cavity generated in human dental enamel by laser thermal evaporation using the Cu-HyBrID laser. The results expos...

Tooth formation begins with the bud stage during which the dental lamina (derived from epithelial tissue) produces a series of tooth buds along its buccal margin. This is followed by the cap stage in which a coned structure, termed the enamel organ, is formed by an invagination of mesenchymal tissue into the tooth bud. All deciduous teeth and permanent molars are derived from the enamel organ o...

Enamel microabrasion has become accepted as a conservative, nonrestorative method of removing intrinsic and superficial dysmineralization defects from dental fluorosis, restoring esthetics with minimal loss of enamel. However, it can be difficult to determine if restoration is necessary in dental fluorosis, because the lesion depth is often not easily recognized. This case report presents a met...

AIM OF THE STUDY Chemotherapeutic treatment in children and adolescents carries a risk of congenital tooth disorders and dentinoma. Study objective is to assess the correlation between tooth abnormalities, early complications of multidrug chemotherapy, and chemotherapeutics used in different antineoplastic therapies in children and adolescents. MATERIAL AND METHODS Enamel defects (development...

Dental fluorosis is a serious health problem caused by ingestion of fluoride in excess through water, food and air. Fluoride is a controversial trace element, on the one hand for its widely applied beneficial uses, especially in improving dental health and on the other hand for its toxic effects. Fluoride causes dental fluorosis by damaging the enamel-forming cells, called ameloblasts. The dama...