early life events influence life-long patterns of emotionality and stress responsiveness and alter the rate of brain and body aging.  much research attention has focused on the programming effects of the hypothalamus pituitary axis (hpa) in early life and on understanding hpa function in response to stressors in adulthood. in comparison, there has been relatively little research on adolescence,...

Introduction: The prostaglandin E2 (PGE2), a cyclooxygenase (COX) product, play critical roles in the synaptic plasticity. Therefore, long term use of COX inhibitors may impair the synaptic plasticity. Considering the wide clinical administration of aspirin and its unknown effects on information processing in the brain, the effect of aspirin and sodium salicylate on the short term synaptic p...

Abstract* Introduction: Chronic morphine exposure can cause addiction and affect synaptic plasticity, but the underlying neural mechanisms of this phenomenon remain unknown. Herein we used electrophysiologic approaches in hippocampal CA1 area to examine the effect of chronic morphine administration on short-term plasticity. Methods: Experiments were carried out on hippocampal slices taken f...

expansive behavior is usually observed in soils, which contain fractions of clay minerals in their composition. water absorption of clay particles and change of natural water content of soil up to plastic limit and down to shrinkage limit will cause significant volume change in expansive soils and will result in severe damages to the structures, buildings and foundations. swelling potential is ...

Grain growth and hardness variation occurring in high-temperature heat affected zone (HAZ) during the welding processes are two thermal dependant aspects of great interest for both academic industrial research activities. This paper presents an innovative finite element (FE) model capable to describe grain decrease that occur gas metal arc (GMAW) commercial AISI 441 steel. The FE software SFTC ...