effects of 28 days lead acetate (ioc, 500, 1000 ppm) treatment on hypertension ami relationship between blood lead levels and hypertension in male. spraguc-dawley rats were studied. results of this study showed tlxat lead acetate treatment did run decrease, body wcight or water consumption, except for lead acetate (1000 ppm) and sodium acetate (500 ppm) which increased fluid consumption when co...

The effects of chronic morphine administration on the development of long-term potentiation (LTP) were investigated at the Schaffer collateral-CA1 pyramidal cell synapses of the rat hippocampal slices using primed-bursts tetanic stimulation. Significant enhancement of orthodromic population spike (OPS) was found for all stimulus intensities after tetanic stimulation. OPS enhancement was greates...

the hypotensive effect of garlic has been well-documented in human subjects and animals. since endothelial activity regulates vascular reactivity in physiological and pathophysiological conditions, the aim of the present study was to investigate the effect of garlic on endothelium-dependent and independent relaxation of rat aorta for elucidation of mechanism of the garlic anti-hypertensive effe...

Our goal was to determine whether exercise training (ExT) alleviates impaired nitric oxide synthase (NOS)-dependent dilation of pial arterioles during chronic exposure to nicotine. We measured dilation of cerebral (pial) arterioles in sedentary and exercised control and nicotine-treated (2 mg·kg(-1)·day(-1) for 4 wk via an osmotic minipump) rats to an endothelial NOS (eNOS)-dependent (ADP), a n...

Heinsia crinata (Afzel.) G. Taylor (Rubiaceae) and Lasianthera africana. P.Beav (Stemonuraceae), which are common vegetables employed in the preparation of soups by Ibibios also used as medicine traditionally to treat variousdiseases including diabetes, were investigated for effect on alpha amylase glucosidase enzymes. H. crinata(450, 900, 1350 mg/kg) L. africana (250, 500, 750 leaves extracts ...

objective(s): there is controversial evidence about the effect of methamphetamine (meth) on spatial memory. we tested the time- dependent effects of meth on spatial short-term (working) and long-term (reference) memory in meth –sensitized and withdrawn rats in the morris water maze. materials and methods: rats were sensitized to meth (2 mg/kg, daily/5 days, sc). rats were trained in water maze ...