BACKGROUND Serological studies indicate that evidence of coeliac disease (CD) exists in about 1% of all children, but we lack estimates of current diagnostic patterns among children and how they vary by socioeconomic group. METHODS We identified all children aged 0-18 years between 1993 and 2012 who were registered with general practices across the UK that contribute to a large population-bas...

OBJECTIVES To develop and optimise a primary care-based complex intervention (CARE Plus) to enhance the quality of life of patients with multimorbidity in the deprived areas. METHODS Six co-design discussion groups involving 32 participants were held separately with multimorbid patients from the deprived areas, voluntary organisations, general practitioners and practice nurses working in the ...

Evidence suggests that urban regeneration programs can stimulate leisure-time walking (LTW) in deprived areas. However, underlying pathways remain unclear. This study explored how urban regeneration might stimulate LTW among adults in deprived areas. We conducted a realist review, a theory-driven approach to evidence synthesis that focuses on mechanisms. We searched three electronic databases f...

BACKGROUND Area deprivation negatively affects health and lifestyles, among which child behaviours. The latter may aggravate the effects of area deprivation on parental health due to higher rates of parenting stress. However, evidence on the influence of the living environment on parenting stress is mostly lacking. The aim of this study was to examine the impact of area deprivation and urbaniza...