M.E. Spector K.K. Gallagher J.B. McHugh S.K. Mukherji SUMMARY: HNSCC that involves the skin is able to invade the dermal lymphatic system. Currently there is no way to identify patients with dermal lymphatic invasion preoperatively. The purpose of this study is to determine whether CT can predict dermal lymphatic invasion. Medical records, CT scans, and corresponding histopathologic slides were...

BACKGROUND Cranial dermal sinuses are rare and occur most frequently in the posterior fossa and along the midline. Likewise, supratentorial dermoid cysts are very uncommon. METHOD We report a unique case of an adult female patient with both a supratentorial dermoid cyst and an incomplete dermal sinus tract. RESULTS The patient is a 31-year-old female, who presented with a new onset complex ...

INTRODUCTION In esthetic treatments with dermal fillers, increasing numbers of physicians are using the technique of mixing an anesthetic agent into the dermal filler before treatment to increase the comfort of the patients. This study aimed at evaluating the effects on the physical properties of a polycaprolactone (PCL)-based dermal filler after mixing with lidocaine. METHODS A range of 2.0%...

Monocytic sarcoma is a neoplasm of immature monocytes involving any extramedullary site such as skin. The definite diagnosis is important for adequate therapy, which is often delayed becauseof misdiagnosis. We report a 51-Year-old diabetic woman who presented with several erythematous itchy papules and plaques on her s...

Labskin is a commercial 3D in vitro skin model based on the original Leeds Model specifically developed for studying interactions between the skin and its microbiome. Further development of the microbiology protocols for growth, preparation, inoculation, and recovery have enabled Labskin to be used for a wide variety of applications in skin microbiology. The method of construction of the model ...

Over the past decade, protein and genetic abnormalities have gradually been unveiled for most types of hereditary epidermolysis bullosa (EB). Much understanding has been gained regarding the underlying pathogenic mechanisms of this group of diseases. To appreciate these new advances and their clinical applications, it is important to understand the basic molecular organisation of the normal der...