PURPOSE To evaluate in-office dermatophyte test medium (DTM) culture as an alternative to traditional laboratory fungal culture for confirming a diagnosis of onychomycosis, and to determine the prevalence of dermatophytes as a cause of onychomycosis in patients not participating in a clinical trial. DESIGN This nationwide multicenter prospective study enrolled 1100 adult patients with suspect...

By means of UV radiation 74 physiological mutants of the dermatophyte Trichophyton mentagrophytes (Robin) Blanchard were induced. These mutants had changed optimum cultivation temperature and mostly changed morphology and sporulation as well.

Dermatophyte test media (DTM) and Sabouraud's dextrose agar (SDA) are well established media for recovery of dermatophytes from clinical samples of dermatophytosis. Skin, hair and nail samples were mycologically examined from 112 patients attending Outpatient Clinic of Dermatology and Veneriology in Mansoura University Hospital in an attempt to compare dermatophyte identification media (DIM) wi...

Tinea manuum is a fungal infection of the hands caused by dermatophytes. It can present with erythema and minimal scale on the dorsum of the hand. However, chronic tinea manuum lesions located on the palmar region may be scaly and hyperkeratotic. Tinea manuum usually affects the dominant hand but it can also occur bilaterally. The term ‘tinea incognito’ is used to describe a dermatophyte infect...

The dermatophyte, Micros porum audouinii, is the most common cause of epidermic tinea capitis of children in this country. Epidemics involving thousands of school children have been reported from all parts of the United States. This fungus is considered by most investigators to be anthropophilic. However, there are recorded in the literature three cases of lower animal infections. In two instan...

BACKGROUND The cutaneous mycoses, mainly caused by dermatophyte fungi, are among the most common fungal infections worldwide. It is estimated that 10% to 15% of the population will be infected by a dermatophyte at some point in their lives, thus making this a group of diseases with great public health importance. OBJECTIVE To analyze the clinical, epidemiological, and therapeutic profile of d...

Dermatophytes are a group of filamentous fungi that cause infections of the skin (see Figure 1 for diseases, Figure 2 for typical dermatophyte species). Diseases caused by dermatophytes include athlete’s foot, ringworm, jock itch, and nail infections (onychomycosis). The medical terminology for dermatophyte infections is to use the word tinea (to denote a fungal infection of the skin) followed ...

During primary Trichophyton mentagrophytes infection of strain 2 guinea pigs, the colony-forming units (CFU) of fungi present within the lesion peaked between days 7 and 14, whereas the severity of the lesion itself peaked between days 11 and 16. Concomitant with the latter peak, a pronounced depression in the in vitro mitogenic activity of spleen cells (SPC) and lymph node cells (LNC) was obse...

BACKGROUND In the absence of a functional dermatophyte-specific polymerase chain reaction (PCR), current diagnosis of dermatophytoses, which constitute the commonest communicable diseases worldwide, relies on microscopy and culture. This combination of techniques is time-consuming and notoriously low in sensitivity. OBJECTIVES Recent dermatophyte gene sequence records were used to design a re...

Companion animals, often asymptomatic reservoir of fungi, can be important sources of infection in humans, due to the close contact with their owners. The present study was aimed to assess the occurrence of dermatophytes and other fungi isolated from pet dermatological lesions in Turin, Italy. Dermatological specimens were examined for fungal elements by direct microscopy and cultured to detect...