OBJECTIVES The objective of the study was to find the prevalence of sleep-related disturbances in patients of Eisenmenger syndrome. DESIGN Prospective observational study. SETTING Tertiary care referral centre in North India. PARTICIPANTS The study included 25 patients with Eisenmenger syndrome (mean age 25.2±9.6 years, 18 men) and 12 patients with cyanotic congenital heart disease with p...

Objective: There are different results on low grade inflammation and metabolic syndrome in patients with obstructive sleep apnea (OSA). We investigated the relation between low grade inflammation and metabolic syndrome in patients with OSA. Methods: This study included 78 OSA patients(AHI ≥5) and 28 control group (AHI <5). Clinical information, body mass index (BMI), Epworth Sleepiness Scale we...

Obstructive sleep apnea syndrome (OSAS) is a common disorder that can lead to significant cardiovascular complications. Several studies have reported increased platelet activation and aggregation in patients with OSAS. In this study we aimed to show a correlation between mean platelet volume (MPV) and severity of OSAS in patients with OSAS without any overt cardiac disease or diabetes. The poly...

We present the cases of three children with patent ductus arteriosus (PDA), pulmonary arterial hypertension (PAH), and desaturation. One of them had desaturation associated with atrial septal defect (ASD). His ASD, PAH, and desaturation improved after successful device closure of the PDA. The other two had desaturation associated with Down syndrome. One had desaturation only at room air oxygen ...

Objectives: Nicotine stimulates release of neurotransmitters that regulate the sleep-wake cycle and thereby leads to insomnia. Smoking is associated with upper airway distress; however, its role in severe sleep-related breathing disorders remains controversial. In this study, we investigated effects smoking on obstructive sleep apnea (OSA).Methods: We 1,163 patients diagnosed OSA who underwent ...

BACKGROUND Oxygen desaturation is not uncommon during bronchoscopy. We sought to identify factors predictive of desaturation during flexible bronchoscopy. METHODS Over eight months, we enrolled 137 randomly selected patients who were undergoing fiberoptic bronchoscopy at our medical center. The patients' oxygen saturation was monitored on their arrival and during the procedure by finger pulse...

Early experience with continuous monitoring of jugular venous oxygen saturation (SjvO2) suggested that this technology might allow early identification of global cerebral ischaemia in patients with severe head injury. The purpose of the present study was to examine the relationship between episodes of jugular venous desaturation and neurological outcome. One hundred and sixteen severely head-in...