Sulforaphane increases the expression of dihydrotestosterone (DHT)-degrading enzyme, 3α-hydroxysteroid dehydrogenase (3α-HSD) in liver, which accelerates DHT degradation, thereby inhibiting hair loss animal model. In this study, we elucidated its underlying mechanism and demonstrated that sulforaphane has inhibitory functions RAW264.7 macrophage cells Hepa1c1c7 at cellular gene levels. The leve...

The discovery that the absorption bands at 293, 281-5 and 271 m,u. (Heilbron, Kamm & Morton, 1926, 1927) present in fractions obtained in the recrystallization of cholesterol were shown very strongly by ergosterol (Rosenheim & Webster, 1927) focused interest on the latter and culminated in the isolation ofcalciferol (vitamin D2). Some time later it was recognized that 7-dehydrocholesterol was a...

Abstract Every year, the number of cases hypersensitivity to insect bites increases. Thus, particular attention needs be paid treatment allergy in children, as scratching can complicate healing process and lead infection. Therefore, a topical issue for modern medicine pharmacy is development gel combined anti-allergic, reparative anti-inflammatory action local manifestations allergic skin react...

INTRODUCTION Carotenoids are plant pigment with important biological activities in humans, such as provitamin-A among others. At present, there are no individual carotenoid intake data in the Dominican population, which is at risk of vitamin A deficiency and has an important percentage of overweight and obese individuals . OBJECTIVE To assess the individual components of vitamin A intake (ret...

Since 1934, when it was shown that ergosterol is not the only provitamin D occurring in nature (l), the provitamin D content of the mixed sterols from many sources has been investigated (2-6). It has been found that the sterols from many of the invertebrates contain a surprisingly large amount of provitamin D as measured spectroscopically. Windaus (3) and Bock and Wetter (4) were able to isolat...

OBJECTIVE To characterize the relationship between serum carotenoids, retinol and anaemia among pre-school children. DESIGN A cross-sectional study was conducted in two groups: anaemic and non-anaemic. Serum levels of retinol, α-carotene, β-carotene, β-cryptoxanthin, lycopene, lutein and zeaxanthin were measured in the study subjects. SETTING Six rural communes of Dinh Hoa, a rural and moun...

Background. Programs of preclinical safety studies the health care products depend on regulatory status investigated products. The classification such products, in particular suppositories for rectal and vaginal use, is a critical step developing tactics their biological evaluation. Adaptation evaluation methods medical devices based combination biologically active substances, as well results u...