background in order to detect nephropathy, measurement of total (24 hrs) urinary albumin or albumin/creatinin ratio in random urine samples is being recommended. but methods of albumin measurement are not available in all laboratories and also cost about 6 times more than that of urinary total protein measurement. objectives this study was performed to determine appropriate cut off point in 24 ...

objectives: to evaluate the effect of two simultaneous protocols in reducing recovery time and assessment of adverse effects of different fluid replacement therapy in management of diabetic ketoacidosis. materials and methods: in this randomized clinical trial study, two standard protocols were chosen to evaluate recovery time and incidence of dka complications. results: 18 subjects who had sev...

conclusions cu, zn and cr play a specific role in the pathophysiology of diabetic nephropathy. meanwhile in these patients, low serum levels of cu, zn and cr were not associated with factors such as drinking water. possible causes should be sought in other factors like urine, intervention factors in absorption and utilization and individual conditions. results mean ± sd levels of zn, cu and cr ...

the search for indigenous natural antidiabetic agents is still ongoing. securigera securidaca seeds are reputed in folk medicine for their value as an antidiabetic remedy, so the present study was carried out to investigate the hypoglycemic efficacy in both normal and streptozotocine (stz)-induced diabetic rats. hydroalcoholic extract of the seeds were administered orally with doses of 200, 400...

objectives due to the known anti-oxidant and anti-diabetic effects of origanum majorana (om), this study was conducted to survey its effects on oxidative stress and histopathology of renal tissue among diabetic rats. materials and methods in this experimental investigation, 32 male rats, weighing 200 - 250 g, were divided into four groups: 1: control, 2: control receiving treatment with om, 3: ...

objective(s):painful diabetic neuropathy is associated with hyperexcitability and hyperactivity of spinal cord neurons. however, its underlying pathophysiological mechanisms have not been fully clarified. induction of excitatory/inhibitory neurotransmission imbalance at the spinal cord seems to account for the abnormal neuronal activity in diabetes. protective properties of neurosteroids have b...

objective(s) oxidative stress plays an important role in diabetic nephropathy pathogenesis. rosmarinic acid, a plant phenolic compound, was first used as an antioxidant agent for inhibition of diabetic nephropathy. material and methods forty male rats were uninephrectomized from the left flank.the rats were divided in four groups randomly; group one as control, group two diabetic untreatment, g...

we report a catalase-negative staphylococcus aureus isolated from a 56-year-old male diabetic patient with foot ulcer who attended our surgery ward. species identification was confirmed by gram staining, standard biochemical tests and pcr amplification of the nuc and fem genes. antibiotic susceptibility showed that the strain was sensitive to imepenem, chloramphenicol, amoxicillin, vancomycin a...

purpose: to evaluate the effectiveness of pars plana vitrectomy and posterior hyaloid stripping in decreasing macular thickness and improving vision in diabetic macular edema.          methods: this prospective interventional case series includes 30 eyes of 25 diabetic patients with diabetic macular edema with macular thickness exceeding 170 microns and thickened posterior hyaloid. bcva and mac...

introduction: diabetic retinopathy (dr) is one of the most serious and most frequent eye diseases in the world and the most common cause of blindness in adults between 20 and 60 years of age. following 15 years of diabetes, about 2% of the diabetic patients are blind and 10% suffer from vision impairment due to dr complications. this paper addresses the automatic detection of microaneurysms (ma...