Patients 75 patients with diabetes who had clinically significant loss of protective sensation ( > 25 V) as measured with a biothesiometer, >1 palpable foot pulse or a transcutaneous oximetry measurement > 40 mm Hg at the dorsum of the fore foot, and a superficial neuropathic plantar diabetic foot ulcer corresponding to grade 1A (University of Texas Diabetic Wound Classification System). Exclus...

Prompt clinical diagnosis and timely treatment are the hallmarks of the proper care of diabetic patients with foot infections. The importance of careful clinical foot examination cannot be overemphasized. When infection is suspected, effort should be made to search for deeper infections, especially osteomyelitis. Numerous imaging techniques are available, but their cost-effectiveness has not be...

Patients: 85 patients 18–80 years of age (mean age 55 y, 51% men) who had diabetes (World Health Organization criteria) and were at high risk of developing diabetic foot ulcerations (International Working Group on the Diabetic Foot risk group 2 or 3—ie, history of foot ulceration or lower extremity amputation, or peripheral sensory neuropathy with loss of protective sensation or foot deformity ...

Diabetic foot ulcers occur in 1.9% of adults with diabetes annually [1], resulting in amputation in 15%– 20% of patients within 5 years [2]. Direct medical costs for diabetic ulcer care represent the majority of the estimated $4.6–$13.7 billion US annual expenditure for diabetic peripheral neuropathy [3]. Even modest improvements in the prevention and therapy of diabetic foot ulcers have the po...

INTRODUCTION Diabetes mellitus is a highly prevalent chronic progressive disease with complications that include diabetic-foot ulcers. METHODS Enterococci isolated from diabetic-foot infections were identified, evaluated by macro-restriction analysis, and screened for virulence traits and antimicrobial resistance. RESULTS All isolates were considered multidrug-resistant, cytolysin and gelat...

OBJECTIVES To delineate the epidemiology of Charcot foot in Hong Kong Chinese diabetic patients, and to provide baseline data for benchmarking the clinic service for this special group of patients. DESIGN Retrospective cohort study. SETTING Regional hospital, Hong Kong. PATIENTS Diabetic patients with Charcot foot and age- and sex-matched diabetic foot clinic attendees between 1995 and 20...

UNLABELLED Vertebral osteomyelitis (or spondylodiscitis) is steadily increasing in Western countries and often results from hematogenous seeding, direct inoculation during spinal surgery, or contiguous spread from an infection in the adjacent soft tissue. We present the case of a 67-year-old white patient with type 2 diabetes who went to Hospital for high fever, back pain, and worsening of know...

The diabetic foot is a common and severe complication of diabetes comprising a group of lesions including vasculopathy, neuropathy, tissue damage and infection. Vasculopathy due to ischemia is a major contributor to the pathogenesis, natural history and outcome of the diabetic foot. Despite conventional revascularization interventions including angioplasty, stenting, atherectomy and bypass graf...

OBJECTIVE To review underlying causes of diabetic foot ulceration, provide a practical assessment of patients at risk, and outline an evidence-based approach to therapy for diabetic patients with foot ulcers. QUALITY OF EVIDENCE A MEDLINE search was conducted for the period from 1979 to 1999 for articles relating to diabetic foot ulcers. Most studies found were case series or small controlled...