BACKGROUND Gain-of-function mutations of the nociceptive voltage-gated sodium channel Nav1.7 lead to inherited pain syndromes, such as paroxysmal extreme pain disorder (PEPD). One characteristic of these mutations is slowed fast-inactivation kinetics, which may give rise to resurgent sodium currents. It is long known that toxins from Anemonia sulcata, such as ATX-II, slow fast inactivation and ...

We use the introduction of diagnosis related groups (DRGs) in German neonatology to study the determinants of upcoding. Since 2003, reimbursement is based inter alia on birth weight, with substantial discontinuities at eight thresholds. These discontinuities create incentives to upcode preterm infants into classes of lower birth weight. Using data from the German birth statistics 1996-2010 and ...

Very deep near-infrared observations in the Faint InfraRed Extragalactic Survey (FIRES) have recently uncovered a significant population of red galaxies at redshifts z > 2. These distant red galaxies (DRGs) are efficiently selected by the criterion Js−Ks > 2.3. We use Chandra data to examine the X-ray emission from DRGs in the 5×5 FIRES MS 1054–03 field. Two of 40 DRGs with Ks < 22 are detected...

OBJECTIVE To analyze the frequency and length of hospital stays as well as the frequency of diabetes-associated outpatient visits of children and adolescents with type 1 diabetes before and after the introduction of DRGs (diagnosis-related groups) in German hospitals. METHODS For this prospective cohort study, data from 2000 (before introduction of DRGs) to 2008 (after introduction) was extra...

Introduction The thinking behind DRGs contains not only clinical concepts but also ideas drawn from health economics and statistics (particularly sampling theory). One example of the influence of economics is the literature on DRGs in reimbursement systems. DRGs are generally placed between fee for service and risk -adjusted capitation. An example of the influence of statistics is the assumptio...

UNLABELLED Diagnosis related groups (DRGs) are widely used in several countries. Their various versions aim to value the cost of hospital production. In Europe, the patient classification systems and standard weights used are usually the American originals. OBJECTIVES The objective of this study was to analyse the extent to which DRGs and DRG-weights explain patient cost variability. Differen...

Very deep near-infrared observations in the Faint InfraRed Extragalactic Survey (FIRES) have recently uncovered a significant population of red galaxies at redshifts . These distant red galaxies (DRGs) are efficiently z 1 2 selected by the criterion . We use Chandra data to examine the X-ray emission from DRGs in the J K 1 2.3 s s FIRES MS 1054 03 field. Two of 40 DRGs with are detected by Chan...

BACKGROUND This study centered on differences in medical costs, using the Taiwan diagnosis-related groups (Tw-DRGs) on medical resource utilization in inguinal hernia repair (IHR) in hospitals with different ownership to provide suitable reference information for hospital administrators. METHODS The 2010-2011 data for three hospitals under different ownership were extracted from the Taiwan Na...