Dialysis adequacy indices that may be used to evaluate the efficiency of small-solute removal include Kt/V, fractional solute removal (FSR), and equivalent urea clearance (EKR). To analyze possible relationships between those indices, we used the two-compartment variable-volume urea kinetic model to simulate several dialysis modalities: hemodialysis (HD) performed three times or six times weekl...

Significant advances have lead to a greater understanding of the role of the complement system within nephrology. The success of the first clinically approved complement inhibitor has created renewed appreciation of complement-targeting therapeutics. Several clinical trials are currently underway to evaluate the therapeutic potential of complement inhibition in renal diseases and kidney transpl...

BACKGROUND Complementary and Alternative Medicines (CAMs) are increasingly practiced in the general population; it is estimated that over 30% of patients with chronic diseases use CAMs on a regular basis. CAMs are also used in hospital settings, suggesting a growing interest in individualized therapies. One potential field of interest is pain, frequently reported by dialysis patients, and seldo...

BACKGROUND Interventional treatment of coronary insufficiency is underemployed among dialysis patients. Studies confirming its efficacy in this set of patients are scarce. OBJECTIVE To assess the results of interventional treatment of coronary artery disease in patients undergoing dialysis. METHODS A total of 34 dialysis patients submitted to coronary angiography between September 1995 and ...

Acute kidney insufficiency (AKI) occurs frequently in intensive care units (ICU). In the management of vascular access for renal replacement therapy (RRT), several factors need to be taken into consideration to achieve an optimal RRT dose and to limit complications. In the medium and long term, some individuals may become chronic dialysis patients and so preserving the vascular network is of ma...

Abstract Background Patient activation in chronic kidney disease (CKD) is increasingly being prioritized and considered a quality metric CKD. Given the importance of patients’ improving care, this study aimed to assess levels its relationship with self-efficacy among patients undergoing hemodialysis. Methods In cross-sectional study, total 180 maintenance hemodialysis were selected by random sa...

C3 glomerulopathy (C3G) is characterized by C3 deposits with minimal immunoglobulin deposition caused by alternative complement pathway dysregulation. Unfortunately, no therapeutic intervention has consistently improved outcomes for patients with C3G. Eculizumab, a monoclonal antibody to C5, is currently the only approved complement-specific agent with some efficacy in the treatment of C3 glome...

Treatment of kidney diseases with a combination therapy of allopathic and traditional medicines with special reference to the role herbal medicines in maintaining serum creatinine and Serum Urea Levels without the dialysis procedures, thereby the patient benefits in less dependence on dialysis and treatment. The aim of this study was to determine the long-term efficacy of hero-mineral preparati...