The Cover Feature shows the production of adipic acid by a two-step pathway from 2,5-furandicarboxylic via tetrahydrofuran-2,5-dicarboxylic over recyclable Ru/Al2O3 catalyst in ionic liquid. More information can be found Research Article A. V. Tran, S.-K. Park, et al.

The synthesis and NOE-based structural characterization is described of thiacalix[4]arene tricarboxylic acid (7), thiacalix[4]crown-5 and -6 monocarboxylic acids (2 and 5), and the bis(N-methylsulfonyl)thiacalix[4]crowns-5 and -6 (4a,b). The 226Ra2+ selectivity coefficients, log(K(Ra)ex/K(M)ex), of the new thiacalix[4]arene derivatives are compared directly with those of thiacalix[4]crown-5 and...

Electrocyclic reaction product of 1-(methoxycarbonyl)-1,2-dihydropyridine was stereospecifically converted by RuO(4) oxidation into azetidine-cis-2,3-dicarboxylic acid.

In silico screening was performed to search for binary solids in which a phenylpiperazine-derivative drug was cocrystallized with a dicarboxylic acid. The phenylpiperazine derivative could be any of 61 such drugs, while the dicarboxylic acid could be any of nine such acids. The uniqueness of this approach was that two criteria had to be fulfilled simultaneously, namely a high propensity for coc...

The metabolism of benzo[a]pyrene (BP) is known to lead to a large number of oxygenated compounds, some of which can bind covalently to DNA. We have studied the integrated metabolism of BP in vivo in germ-free rats given (14)C-labeled BP. Urinary metabolites were separated into groups according to acidity using lipophilic ion exchangers. The groups were analyzed by mass spectrometry and were fur...

A series of isoquercitrin (quercetin-3-O-β-d-glucopyranoside) esters with mono- or dicarboxylic acids was designed to modulate hydro- and lipophilicity and biological properties. Esterification of isoquercitrin was accomplished by direct chemoenzymatic reaction using Novozym 435 (lipase from Candida antarctica), which accepted C₅- to C12-dicarboxylic acids; the shorter ones, such as oxalic (C₂)...

Biosynthesis of griseolic acids, competitive inhibitors of cyclic nucleotide phosphodiesterase, was investigated with the culture of a producing strain of Streptomyces griseoaurantiacus. 13C-Labeled and 15N-labeled compounds were added into the culture, and 13C-enriched and 15N-enriched griseolic acid A was isolated from the culture medium and analyzed by 13C NMR and 15N NMR spectroscopy. The c...

The performance of non-fullerene, polymer bulk heterojunction (BHJ) organic photovoltaic devices has a significant correlation with the molecular morphology donor and acceptor. authors show that small molecules coordinated to metal oxide, an electron transport seed layer (ETSL), can profoundly modify donor:acceptor inverted (OPV) devices. Using grazing incidence wide angle X-ray scattering (GIW...