OBJECTIVE The aim of this study was to investigate the effect of apolipoprotein (apo)E4 allele on plasma LDL cholesterol response to calorie-restricted diet therapy in type 2 diabetic patients. RESEARCH DESIGN AND METHODS Twenty-four diabetic patients with the apoE3/3 genotype and 11 diabetic patients with the apoE4/3 genotype were recruited. Participants were hospitalized for calorie-restric...

OBJECTIVE This study examines the effects of circuit-type resistance training on the need for insulin in women with gestational diabetes mellitus. STUDY DESIGN Thirty-two patients with gestational diabetes mellitus were randomly assigned either to a group that was treated with diet alone or to a group that was treated with diet plus resistance exercise. RESULTS The number of women whose con...

PURPOSE We aimed to study whether ketogenic diet (KD) therapy leads to resolution of super-refractory status epilepticus in pediatric patients without significant harm. METHOD A retrospective review was performed at Phoenix Children's Hospital on patients with super-refractory status epilepticus undergoing ketogenic diet therapy from 2011 to 2015. RESULTS Ten children with super-refractory ...

how to cite this article: ghazavi a, tonekaboni sh, karimzadeh p, nikibakhsh aa, khajeh a, fayyazi a. the ketogenic and atkins diets effect on intractable epilepsy: a comparison. iran j child neurol. 2014 summer;8(3): 12-17. abstract objective intractable epilepsy is a major difficulty in child neurology, because the numbers of drugs that are available for treatment are limited and new treatmen...

BACKGROUND Management of glioblastoma multiforme (GBM) has been difficult using standard therapy (radiation with temozolomide chemotherapy). The ketogenic diet is used commonly to treat refractory epilepsy in children and, when administered in restricted amounts, can also target energy metabolism in brain tumors. We report the case of a 65-year-old woman who presented with progressive memory lo...

ATP and adenosine are purines that play dual roles in cell metabolism and neuronal signaling. Acting at the A(1) receptor (A(1)R) subtype, adenosine acts directly on neurons to inhibit excitability and is a powerful endogenous neuroprotective and anticonvulsant molecule. Previous research showed an increase in ATP and other cell energy parameters when an animal is administered a ketogenic diet,...

hypertension is a common health problem. hypotensive drugs and low salt diet are used in its treatment. this study was designed to compare the effectiveness of a low-salt diet and drug therapy in the treatment of arterial hypertension. a total of 256 randomly selected patients with essential hypertension consulting the non-contagious diseases clinic in shahreza, isfahan, iran, were included in ...

Semaglutide (Wegovy) is a GLP-1 analogue indicated as an adjunct to diet and physical activity for weight management in adults who are overweight or obese. This article discusses its efficacy, adverse effects place therapy.