PURPOSE The expression of glucose transporter-1 (Glut-1) gene and those of major thyroid-specific genes were examined in papillary carcinoma tissues, and the expressions of these genes were compared with cancer differentiation grades. MATERIALS AND METHODS Twenty-four human papillary carcinoma tissues were included in this study. The expressions of Glut-1- and thyroid-specific genes [sodium/i...

INTRODUCTION Anaplastic transformation of well-differentiated papillary thyroid carcinoma at distant metastasis sites is rare. To the best of our knowledge, this is the first report of an autopsy case of anaplastic transformation of papillary thyroid carcinoma in multiple lung metastases presenting with a malignant pleural effusion. CASE PRESENTATION We report an autopsy case of a 61-year-old...

Thyroid carcinoma is the commonest endocrine malignancy. The majority of these are differentiated thyroid carcinomas, which have a good overall prognosis. Treatment includes surgical excision, radio-iodine ablation and long-term thyrotropin suppression. The degree and length of suppression required, as well as the potential side-effect remain controversial. Therefore, the aim of this study was ...

Differentiated thyroid carcinomas, particularly papillary carcinoma, are the tumors with good prognosis, but sometimes have a tendency to spread into the surrounding tissue. The spread of these tumors usually involves muscle, cartilage and upper aerodigestive tract. During two years (2008-2009) at the Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Center Zagreb, 2...

Papillary thyroid carcinoma is the most common form of differentiated thyroid carcinoma. It is generally confined to the neck with or without spread to regional lymph nodes. Metastatic thyroid carcinomas are uncommon and mainly include lung and bone. Metastases involving oral and maxillofacial region are extremely rare. We described a case of malar metastasis revealing a follicular variant of p...

INTRODUCTION The most common site of metastases in differentiated thyroid carcinomas is the lungs. In our study, we aimed to determine the ratios of lung metastases in patients with differentiated thyroid carcinoma and response to radioiodine therapy. MATERIAL AND METHODS A total of 542 patients with differentiated thyroid carcinoma who were admitted to our clinic were included in the study. ...

Prof. YJ Park, deputy editor of ‘Endocrinology and Metabolism,’ wrote a review on the prevalence of, and risk factors for, subclinical thyroid disease in Korea; this analysis was particularly clear [1]. Several review articles on thyroid cancer appeared in the third issue of 2014: “Molecular pathogenesis and targeted therapies in well-differentiated thyroid carcinoma”; “Current status and futur...

introduction: cauda equina secondary to metastatic follicular thyroid cancer of the lumbosacral area is a rare entity.   case report: we report an unusual case of a 52-year-old male who presented with backache, lower limb weakness, and perianal numbness. a ct-scan of the lumbosacral area showed an enhancing mass at the l4, l5 and s1 vertebrae. histopathology after excision revealed a metastatic...