Melanin is a pigment that contributes to our skin color. Hyperpigmentation where melanin is produced in excess quantity can cause significant esthetic problem. Facial aesthetics is affected by smile line. Gingiva is an integral component of facial esthetics. Hyperpigmentation in gingiva affects facial esthetics. Various surgical modalities have been employed to correct hyperpigmentation. But, r...

Naevus of Ota (naevus fusculocoeruleus ophthalmomaxillaris) was described by the Japanese dermatologist, Ota, in 1939 as a dermal melanocytic hamartoma that presents as bluish hyperpigmentation along the ophthalmic, maxillary, and mandibular branches of the trigeminal nerve. It is bilateral in less than 5% cases, occurring frequently in Orientals (0.2%–1%) and darker races and rarely in white p...

BACKGROUND Poland's Syndrome (PS) is a rare congenital syndrome characterized by the unilateral partial or complete absence of the sternocostal head of the pectoralis major muscle and ipsilateral brachysyndactyly or syndactyly of the fingers. It has been reported to be associated with other diseases, but PS accompanied by neurofibroma has rarely been reported. CASE REPORT We report a rare cas...

Scleromyxedema is a chronic, progressive condition characterised by dermal fibrosis and mucinosis. The clinical variants consist of generalised confluent lichenoid eruptions (scleromyxedema) with systemic manifestations and a localised variant with discrete papular eruptions. The cases which do not fit into either of the category are termed as atypical or intermediate form. We report such a cas...

Oculoectodermal syndrome is a rare disease characterized by the association of aplasia cutis congenita, epibulbar dermoids, and other abnormalities. This report describes the twentieth case of the disease. We report a 4-year-old female child who presented with the classical features of the syndrome: aplasia cutis congenita and epibulbar dermoids. Our case expands the clinical spectrum of the di...

A 28-year-old female patient with disseminated tuberculosis and choroidal tubercles on a regimen of systemic antitubercular therapy underwent fundus photography and optical coherence tomography (OCT). This was carried out monthly until complete healing of the tubercle was seen. The tubercle consisted of a central white-yellow core, consistent with choroiditis, with a faint hyperpigmentation sur...

INTRODUCTION Whipple's disease is a chronic, multisystem, infectious disease caused by Tropheryma whipplei. It most commonly affects Caucasian males, middle-aged. Morbus Whipple is primarily gastrointestinal disease, manifested as malabsorption syndrome, and diagnosed by endoscopy and intestinal biopsy. Extraintestinal manifestations are not rare. CASE REPORT A 48-year-old male was admitted d...

Diffuse cutaneous hyperpigmentation may have various causes: endocrine, metabolic, autoimmune, melanosis secondary to metastatic melanoma, drug or heavy metal poisoning. A cause to remember is acanthosis nigricans, which, in the form of paraneoplastic syndrome may be the first or even the only clinical manifestation of a cancer. The most common cause of malignant acanthosis nigricans is the gas...

Acanthosis nigricans (AN) is a skin disorder characterized by focal or diffuse hyperkeratosis symmetric hyperpigmentation of the skin and oral cavity mucosa. Various neoplasms, especially gastrointestinal adenocarcinomas are associated with acanthosis nigricans (AN malignant). Chemotherapy may cause regression of skin lesions. The etiology of AN is not clear. A role of growth factors such as me...