BACKGROUND AND PURPOSE Functional correlates of microstructural damage of the brain affected by MS are incompletely understood. The purpose of this study was to evaluate correlations of visual-evoked potentials with microstructural brain changes as determined by DTI in patients with demyelinating central nervous disease. MATERIALS AND METHODS Sixty-one patients with clinically isolated syndro...

Oxygen diffusion would not be important for healthy concrete. Once concrete is carbonated, however, oxygen diffusion is very crucial to lead reinforcement corrosion. Therefore, oxygen is always a potential threat of reinforcement corrosion in concrete and oxygen diffusivity is a material parameter for service life determination and durability designing of the concrete. One of the simple approac...

BACKGROUND Quantitative fiber tracking derived from diffusion tensor imaging (DTI) was used to determine whether white matter association, projection, or commissural tracts are affected in nondemented individuals with HIV infection and to identify the regional distribution of sparing and impairment of fiber systems. METHODS DTI measured fractional anisotropy and diffusivity, quantified separa...

Experimental measurements of the diffusion coefficient of human methemoglobin were made at 25 degrees C with a modified Stokes diaphragm diffusion cell. A Millipore filter was used in place of the ordinary fritted disc to facilitate rapid achievement of steady state in the diaphragm. Methemoglobin concentrations varied from approximately 5 g/100 ml to 30 g/100 ml. The diffusion coefficient in t...

Electromigration driven void dynamics plays an important role in the reliability of copper interconnects; a proper understanding of which is made more difficult due to local variations in line microstructure. In simulations, the parameter which best incorporates these variations is the effective atomic diffusivity D eff which is sensitive to grain size and orientation, interface layer thickness...

Using the technique of optical mixing spectroscopy, we have observed the Brownian movement and measured the diffusivity of proteins within whole, intact human and bovine lenses. The magnitude and the temperature dependence of the protein diffusivity in bovine and normal human lenses implies that cold cataract is the result of a first-order phase separation of the protein-water mixture in the le...

We investigate anchored scroll-wave filaments in an excitable medium whose diffusivity matrix, including its determinant, is spatially nonuniform. The study is motivated by cardiological applications where scroll-wave behavior in the presence of diffusivity gradients is believed to play an important role in the development of severe arrhythmias. A diffusivity gradient is expected to make the fi...

Diffusion tensor imaging (DTI) and immunohistochemistry were used to examine axon injury in the rat spinal cord after unilateral L(2)-L(4) dorsal root axotomy at multiple time points (from 16 h to 30 d after surgery). Three days after axotomy, DTI revealed a lesion in the ipsilateral dorsal column extending from the lumbar to the cervical cord. The lesion showed significantly reduced parallel d...

Trigeminal neuralgia is characterized by facial pain that may be sudden, intense, and recurrent. Our aim was to investigate microstructural tissue changes of the trigeminal nerve in patients with trigeminal neuralgia resulting from neurovascular compression by diffusion tensor imaging, and to test the predictive value of diffusion tensor imaging for determining outcomes after radiofrequency rhi...