From the Liver Disease Research Branch, Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases (J.H.H.), and the Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (R.H.P.), National Institutes of Health, Bethesda; and the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Bal...

OBJECTIVES To assess the economic impact, research output and research support of digestive diseases, and to compare them to those of other common disease entities, specifically mental, cardiovascular, respiratory, and central nervous system diseases. METHODS Economic burden was assessed with the use of (a) published Canadian government data of direct cost from 1963 to 1993, (b) data from the...

NATIONAL INSTITUTES OF HEALTH Cigarette smoking causes a variety of lifethreatening diseases, including lung cancer, emphysema, and heart disease. An estimated 400,000 deaths each year are caused directly by cigarette smoking. Smoking is responsible for changes in all parts of the body, including the digestive system. This fact can have serious consequences because it is the digestive system th...

DNA extracted from peripheral blood of two Ecuadorian patients showing severe digestive pathology was amplified by the polymerase chain reaction using a Trypanosoma cruzi specific oligonucleotide primers derived from the primary sequence of a cDNA encoding for a 24 kDa excretory/secretory protein. The positive PCR results together with the clinical findings confirmed that both patients had a di...

Recently, a draft of the report of the National Commission on Digestive Diseases was made available to the public. The Commission was given the task of assessing the current state of science in digestive diseases research, and developing a 10-year plan for digestive diseases research consistent with National Institutes of Health (NIH)'s mission of improving the health of the nation through rese...

â  upper gastrointestinal tract (gastroduodenal) crohn’s disease (cd) is an uncommon condition, occurring in about 1-5% of all cd cases. our case was an extremely rare manifestation of cd, who presented with distal duodenal obstruction. as preoperative diagnosis was not estabâ­lished he underwent segmental resection and end-to-end anastomosis. postoperative small bowel fistulae were not obser...

BACKGROUND Digestive disorders pose significant burdens to millions of people worldwide in terms of morbidity, mortality and healthcare costs. Turmeric has been traditionally used for conditions associated with the digestive system, and its therapeutic benefits were also confirmed in clinical studies. However, rigorous systematic review on this topic is severely limited. Our study aims to syste...

For over 30 years, it has been known that Phakopsora pachyrhizi is unusual in that it penetrates from urediniospores directly through the leaf cuticle without entering stomates. This unusual mode of penetration suggests that disease resistance mechanisms might exist for soybean rust that do not exist for most rust diseases. As a result, we decided to conduct a histological study using transmiss...

Digestive system fistula originates most frequently as a complication after surgical procedures, less often occurs in the course of inflammatory diseases, but it can also result from neoplasm and injuries. THE AIM OF THE STUDY was to analyze the causes and retrospectively assess the perioperative procedures as well as the results of digestive system fistula treatment. MATERIAL AND METHODS. Own ...

The risks of poor transition include delayed and inappropriate transfer that can result in disengagement with healthcare. Structured transition care can improve control of chronic digestive diseases and long-term health-related outcomes. These are the first nationally developed guidelines on the transition of adolescent and young persons (AYP) with chronic digestive diseases from paediatric to ...