background: dyslipidemia is considered an independent risk factor for coronary heart disease (chd). in the present study, we examined lipid profiles and paraoxonase 1 (pon1) activity and atherogenic indexes status and the relationship of pon1 activity by high-density lipoprotein (hdl) and atherogenic indexes in chd patients and healthy people. methods: the aim of the study was to compare pon1, ...

increases in body mass index (bmi) are reported to influence asthma response to treatment. the aim of this study was to investigate the relationship between bmi and response to treatment in a group of patients that were referred for asthma control. effectiveness measurements in this analysis included percentage of changes in forced volume in 1 second (fev1), forced volume capacity (fvc), fev1/f...

conclusions according to the results of the study, abdominal obesity is as a risk factor for atherosclerosis. therefore, the use of a simple, low cost and high precision method for determining visceral obesity and preventing the cad is warranted. background despite efforts made by the medical community and public health officials for combating 76 obesity, the prevalence of overweight and obesit...

We propose a single-index di usion model in this paper. This model can avoid the `curse of dimensionality' in estimating a multivariate nonparametric conditional variance. We adopt an absolute deviation estimation method to estimate the model. Comparing with the commonly used estimators, the absolute deviation estimator is more stable and efcient. Some simulations and applications to real data ...

OBJECTIVE To evaluate the effect of golimumab on physical function, health-related quality of life (HRQOL), and productivity in psoriatic arthritis (PsA). METHODS GO-REVEAL was a multicenter, randomized, placebo-controlled study. Adult patients with active PsA (n = 405) received golimumab (50 or 100 mg) or placebo every 4 weeks, with early escape at week 16 (placebo → 50 mg, 50 → 100 mg) or p...

OBJECTIVES We longitudinally studied outcomes of patients with juvenile idiopathic arthritis (JIA) using the Childhood Health Assessment Questionnaire (CHAQ) for physical disability and the Juvenile Arthritis Damage Index for articular (JADI-A) and extra-articular damage (JADI-E), and we correlated them with various disease activity variables. METHODS Eighty-seven patients with JIA were inclu...

objective(s): iodine-123 metaiodobenzylguanidine (123i-mibg) myocardial scintigraphy has been used to evaluate cardiac sympathetic denervation in lewy body disease (lbd), including parkinson’s disease (pd) and dementia with lewy bodies (dlb). the heart-tomediastinum ratio (h/m) in pd and dlb is significantly lower than that in parkinson’s plus syndromes and alzheimer’s disease. although this ra...

OBJECTIVE Disposition index (DI) and glucose effectiveness (S(G)) are risk factors for diabetes. However, the effect of DI and S(G) on future diabetes has not been examined in large epidemiological studies using direct measures. RESEARCH DESIGN AND METHODS Insulin sensitivity index (S(I)), acute insulin response (AIR), and S(G) were measured in 826 participants (aged 40-69 years) in the Insul...

sturbi cognitivi. La valutazione di efficacia della AAT nel danno cognitivo è frequentemente influenzata da un disegno sperimentale scarso, da cui non emergono evidenze conclusive. Scopo di questo studio era di verificare l’effetto clinico di una AAT a medio termine con cani in pazienti ambulatoriali con lieve danno cognitivo da malattia di Alzheimer (AD) verso un gruppo controllo. Metodi. Lo s...