In this article, we evaluate glycosyl dithiocarbamates (DTCs) with unprotected C2 hydroxyls as donors in β-linked oligosaccharide synthesis. We report a mild, one-pot conversion of glycals into β-glycosyl DTCs via DMDO oxidation with subsequent ring opening by DTC salts, which can be generated in situ from secondary amines and CS2. Glycosyl DTCs are readily activated with Cu(I) or Cu(II) trifla...

Broccoli sprouts are a rich source of glucosinolates and isothiocyanates that induce phase 2 detoxication enzymes, boost antioxidant status, and protect animals against chemically induced cancer. Glucosinolates are hydrolyzed by myrosinase (an enzyme found in plants and bowel microflora) to form isothiocyanates. In vivo, isothiocyanates are conjugated with glutathione and then sequentially meta...

The physical properties of five siloxane polymers with different types and frequencies of amino functional groups along the polymer side chains have been manipulated from flowing liquids to gels and to rubber-like materials by the simple addition or subtraction of a neutral triatomic molecule, CO2 or CS2, at room temperature. The chemical changes, formation of ammonium carbamates and ammonium d...

A dithiocarbamate-based methodology is employed to prepare linked heteromultimetallic complexes and then further exploited in the surface functionalisation of gold nanoparticles.

22 Dupont, G. P., IIuecksteadt, T. P., Marshall, B. C., Ryan, U. S., Michael, J. R. and Iloidal, J. R. (1992) J. Clin. Invest. 89, 197-202 Burdon, R. H., Alliangana, D. and Gill, V. (1995) Free Radic. Res. 23, 471-486 24 Burdon, R. €I. and Gill, V. (1993) Free Radic. Res. Commun. 19,203-213 25 Burdon, R. H., Gill, V. and Rice-Evans, C. (1991) in Oxidative Damage and Repair (Davies, K. J. A., ed...