نتایج جستجو برای: dna fragmentation index dfi
تعداد نتایج: 922525 فیلتر نتایج به سال:
This study was designed to compare the effects of Jinkui Shenqi and Wuzi Yanzong pill on sperm motility DNA fragmentation rate in patients with asthenospermia. 130 cases were randomly divided into an observation control group (n=65). The treated while pill. parameters (PR), semen concentration, motility, DFI α-glucosidase, fructose, seminal plasma zinc (Zn), acid phosphatase (ACP) biochemistry ...
Previous studies have shown that both density gradient centrifugation (DGC) and swim up (SU) procedures can select spermatozoa with longer telomeres for assisted reproduction techniques (ART). However, it is unknown which approach is more effective. The aim of the present study was to compare the effects of these two methods on sperm telomere length (STL). A total of 150 normozoospermic subject...
In this study 60 couples undergoing intracytoplasmic sperm injection (ICSI) procedures were enrolled. All men were classified into two groups regarding to the DNA fractionation index (DFI) threshold value: group I < 15% and group II =or> 15%. In group I, median DFI was 4%, normal pre-implantation embryo development was observed and eleven pregnancies were achieved. In group II, median DFI was 2...
Background: Globozoospermia is an uncommon disorder of sperm morphology associated with severe male infertility. Patients who contain both normal and round-headed sperm are called partial globozoospermic. It is possible that round-headed sperm may have an abnormal chromatin structure and /or DNA strand breaks. Moreover, sperm DNA fragmentation and protamine deficiency is shown to be associated ...
tau.amegroups.com © Translational Andrology and Urology. All rights reserved. The search for the best biomarker for the diagnosis of male infertility is more evident in recent years as conventional semen analysis is not always an optimal predictor of male fertility. Since the advent of the intra-cytoplasmic sperm injection (ICSI) for male factor infertility, the pace of research related to sper...
tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Dr. Ward in his commentary summarized the currently available sperm DNA fragmentation (SDF) tests. He classified the eight SDF assays into four groups based on the different target sites and illustrated the grouping in a diagram to simplify understanding of the readers (1). We would like to supplement, in the followin...
INTRODUCTION Sperm chromatin integrity assessment has been suggested as a fertility predictor. The aim of this study was to examine the relationship between the results of sperm chromatin structure assay (SCSA) and the outcome of IVF, ICSI and intrauterine insemination (IUI). METHODS A total of 306 consecutive couples undergoing assisted reproduction were included. IUI was performed in 131, I...
STUDY QUESTION Does the sperm DNA fragmentation index (DFI) improve depending on the FSH receptor (FSHR) genotype as assessed by the nonsynonymous polymorphisms rs6166 (p.N680S) after 3 months of recombinant FSH treatment in men with idiopathic infertility? SUMMARY ANSWER FSH treatment significantly improves sperm DFI only in idiopathic infertile men with the p.N680S homozygous N FSHR. WHAT...
مقدمه: یکی از عوامل ایجاد کننده آسیب در DNA اسپرم، آپوپتوز است. با توجه به نقش حیاتی میکروRNAها در فرآیندهای مختلف پاتوفیزیولوژیک، احتمال کنترل فرآیند آپوپتوز در DNA اسپرم نیز توسط میکروRNAها مطرح شده است. مطالعه حاضر با هدف تعیین ارتباط میان میزان آسیب DNA اسپرم و سطح بیان miR-15a/16 و ژن ضد آپوپتوز BCL-2 انجام شد. روش‌کار: این مطالعه تجربی در سال 1396 بر روی 30 بیمار مراجعه کننده به مر...
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