Cell confluence induces the activation of signal transducer and activator of transcription-3 (Stat3) in various cancer and epithelial cells, yet the biological implications and the associated regulatory mechanisms remain unclear. Because confluent polarized epithelia demonstrate dome formation and sodium influx that mimic the onset of differentiation, we sought to elucidate the role of Stat3 in...

BACKGROUND A frontoparietal dome of a large pachycephalosaurid collected from the Upper Cretaceous Hell Creek Formation in 2001 is identified as Pachycephalosaurus wyomingensis. The specimen features two large oval depressions on the dorsal surface, accompanied by numerous circular pits on the margin and inner surface of the larger depressions. METHODOLOGY/PRINCIPAL FINDINGS In order to ident...

The effect of exogenous gangliosides on the occurrence of domes in MDCK cell cultures was investigated in view of the involvement of both dome formation and gangliosides in cell growth, differentiation and transepithelial transport. Dome formation was increased by gangliosides in medium free of fetal calf serum. Among the gangliosides tested, GM3 and GD3 isolated from porcine kidney were most a...

Ultrafast high energy electron diffraction in reflection geometry is employed to study the structural dynamics of self-organized Germanium hut-, dome-, and relaxed clusters on Si(001) upon femtosecond laser excitation. Utilizing the difference in size and strain state the response of hut- and dome clusters can be distinguished by a transient spot profile analysis. Surface diffraction from {105}...

Planetariums and smaller personal domes can provide an immersive environment for science education, virtual reality, and entertainment [Shaw 1998]. Digital projection into domes, called “full dome projection” in the industry, can be a technically challenging and expensive exercise, particularly so for installations with modest budgets. An alternative full dome digital projection system is prese...

The optical reference plane of a J1002 shaped dome diffuser from CMS-Schreder was determined using direct normal spectral solar UV irradiance measurements relative to a flat Teflon diffuser. The spectroradiometers were calibrated relative to the same irradiance standard. The optical reference plane of the shaped J1002 diffuser is 5.3 mm behind the top of the dome with an uncertainty of 1.0 mm. ...

BACKGROUND The aim of this study was to confirm that the interstitial cells of Cajal (ICCs) in the dome wall of the bladder are pacemaker cells, and that the dome wall of the bladder acts as a pacemaker site in the detrusor instability (DI) rat model. MATERIAL AND METHODS The model of DI in Wistar rats was established and urodynamic studies measuring the bladder volume and pressure were perform...

Percutaneous hepatic interventions are generally safe given the fact that liver closely abuts the abdominal wall and hence it is easily accessible. However, the superior portion of liver, adjacent to the diaphragm, commonly referred as the "hepatic dome", presents unique challenges for interventionists. Percutaneous access to the hepatic dome may be restricted by anatomical factors and special ...

We present a means of extracting lava dome extrusion rates from data provided by the Thematic Mapper and Enhanced Thematic Mapper Plus instruments flown on the Landsat satellites. Extrusion rates derived from the Landsat data for Santiaguito dome complex (Guatemala) during November 1987 and January 2000 of 0.72€0.08 and 0.48€0.09 m3 s–1 compare favorably with ground-based estimates of 0.63€0.28...

A detailed deuterium excess profile measured along the Dome C EPICA (European Project for Ice Coring in Antarctica) core reveals the timing and strength of the sea surface temperature changes at the source regions for Dome C precipitation. We infer that an Oceanic Cold Reversal took place in the southern Indian Ocean, 800 years after the Antarctic Cold Reversal. The temperature gradient between...