نتایج جستجو برای: donepezil hydrochloride

تعداد نتایج: 45696  

Journal: :Stroke 2003
Sandra Black Gustavo C Román David S Geldmacher Stephen Salloway Jane Hecker Alistair Burns Carlos Perdomo Dinesh Kumar Raymond Pratt

BACKGROUND AND PURPOSE Clinical observations suggest that patients with vascular dementia (VaD) may benefit from treatment with cholinesterase inhibitors. This study evaluated the efficacy and safety of donepezil for relieving symptoms of dementia in VaD. METHODS Patients (n=603; mean age, 73.9 years; 55.2% men) with probable (70.5%) or possible (29.5%) VaD, according to criteria of the Natio...

2017
Martin Knapp Derek King Renée Romeo Jessica Adams Ashley Baldwin Clive Ballard Sube Banerjee Robert Barber Peter Bentham Richard G Brown Alistair Burns Tom Dening David Findlay Clive Holmes Tony Johnson Robert Jones Cornelius Katona James Lindesay Ajay Macharouthu Ian McKeith Rupert McShane John T O'Brien Patrick P J Phillips Bart Sheehan Robert Howard

OBJECTIVE Most investigations of pharmacotherapy for treating Alzheimer's disease focus on patients with mild-to-moderate symptoms, with little evidence to guide clinical decisions when symptoms become severe. We examined whether continuing donepezil, or commencing memantine, is cost-effective for community-dwelling, moderate-to-severe Alzheimer's disease patients. METHODS Cost-effectiveness ...

2012
De-qiang Li Yu-ping Zhou Han Yang

AIM To evaluate the efficacy and safety of donepezil plus natural hirudin in patients with mild-to-moderate Alzheimer's Disease. METHODS In the 20-week, randomized, open-label and controlled study, 84 patients received either donepezil (5 mg/day for the first 4 weeks and 10 mg/day thereafter) or donepezil plus natural hirudin (3 g/day) treatment. Efficacy was reflected by the change of the to...

Journal: :iranian journal of analytical chemistry 2014
azar bagheri gh.

spectrophotometric and electrochemical studies were successfully used in quantitative analysis of amitriptyline hydrochloride (ath) and nortriptyline hydrochloride (nth). conductometric titration were carried out in equeous solution using iodide and dopamine and serotonine as titrant. two new methods using spectrophotometry are dascribed for the determination of (ath) and (nth) with potassium b...

2013
Tomoyuki Nishizaki Takeshi Kanno Akinobu Gotoh

Purpose: Thus far, no promising drug for Alzheimer disease has been developed. Previously, we documented the beneficial effects of 1,2-dilinoleoyl-sn-glycero-3-phosphocholine (DL-PC) and/or 1palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (PO-PC), which enhanced learning and memory abilities and improved cognitive disorders in both animals and humans. The present study reviews the usefulness of ...

Journal: :Brain : a journal of neurology 2004
Andrew J Saykin Heather A Wishart Laura A Rabin Laura A Flashman Tara L McHugh Alexander C Mamourian Robert B Santulli

Cholinesterase inhibitors positively affect cognition in Alzheimer's disease (AD) and other conditions, but no controlled functional MRI studies have examined where their effects occur in the brain. We examined the effects of donepezil hydrochloride (Aricept) on cognition and brain activity in patients with amnestic mild cognitive impairment (MCI), a diagnosis associated with a high risk of dev...

Journal: :Revista Da Associacao Medica Brasileira 2021

SUMMARY OBJECTIVE: To observe the effects of Dengzhan Shengmai capsule combined with donepezil hydrochloride on cognitive function, daily living ability, and safety in patients Alzheimer's disease. METHODS: A total 294 Alzheimer’s disease were randomly divided into a treatment group control group, 147 cases each group. The was given oral 5 mg once day, 0.36 g three times based RESULTS: At 3 6 m...

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