نتایج جستجو برای: dopaminergic neurotransmission
تعداد نتایج: 27281 فیلتر نتایج به سال:
Cell-gene therapy is a dynamic constituent of novel medical biotechnology. Neurodegenerative disordersin which damage to or demise of specific brain cell types plays central role, are clear examples of diseasecandidate for cell replacement therapy. Dopaminergic (DAergic) neurons biosynthesize dopamine, a vitalneurotransmitter in the central nervous system. Due to the involveme...
Dopaminergic neurotransmission mediates a majority of the vital central nervous system functions. Disruption of these synaptic events provokes a multitude of neurological pathologies, including Parkinson's, schizophrenia, depression, and addiction. Growing evidence supports a key role for noncoding RNA (ncRNA) regulation in the synapse. This review will discuss the role of both short and long n...
Accumulating data indicate a common occurrence of tic exacerbations and periods of psychosocial stress. Patients with Tourette's syndrome (TS) also exhibit aberrant markers of hypothalamic-pituitary-adrenal (HPA) axis activation. Based on these findings, a functional relationship between stress and tic disorders has been suggested, but the underlying mechanism of how stress may affect tic patho...
BACKGROUND The complex pharmacological profile of the antiparkinsonian drug budipine influences neurotransmission beyond the dopaminergic system. Previous studies have demonstrated the therapeutic efficacy of budipine on motor symptoms in insufficiently treated patients with Parkinson disease. OBJECTIVE To demonstrate the efficacy of 20 mg of budipine, 3 times daily, in addition to a stable, ...
1. Abstract 2. Introduction 3. Cognition, neurotransmission, and membrane phospholipids in schizophrenia 3.1. Memory impairment in schizophrenia 3.1.1. Systems of memory 3.1.2. Memory deficits in schizophrenia patients 3.1.2.1. Verbal declarative memory 3.1.2.2. Semantic memory 3.1.3. Memory deficits in nonaffected family members of patients 3.2. Association between cognition and neurochemistry...
Dopamine is important to learning and plasticity. Dopaminergic drugs are the focus of many therapies targeting the motor system, where high inter-individual differences in response are common. The current study examined the hypothesis that genetic variation in the dopamine system is associated with significant differences in motor learning, brain plasticity, and the effects of the dopamine prec...
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