OBJECTIVE To determine the appropriateness (both indications and adequate dosage regimen via creatinine clearance estimation) of allopurinol by physicians of different specialties in a tertiary care centre. PATIENTS AND METHODS In this cross sectional study computerized clinical records of 156 adult patients who were prescribed allopurinol from 12th November to 11th December, 2011 were retrie...

conclusions evaluation of iranian traditional dosage forms like vaginal and rectal types could be an attractive topic of research and the current study can briefly represent the iranian traditional pharmaceutical knowledge on vaginal and rectal drug delivery. objectives the aim of this study is the investigation about iranian traditional pharmaceutical dosage forms of vaginal and rectal medicat...

STUDY QUESTION Do parameters which are involved in pathogenesis of polycystic ovarian syndrome (PCOS) predict the dosage of recombinant FSH required to achieve monofollicular development for ovulation induction? SUMMARY ANSWER Anti-Mullerian hormone (AMH) appeared to be an independent predictor of the required dosage of FSH to achieve monofollicular development for ovulation induction in a st...

Responsible self-treatment in chronic diseases involves adjustment of the drug’s dose depending on monitoring data. The aim study was to simulate dosage drugs responsible and find methods for calculating current dosages. methodological basis work were mathematical modeling control theory. case discrete with introduction a feedback loop is considered. A method drug proposed, taking into account ...

BACKGROUND Chemotherapy is not given routinely to patients with malignancies receiving chronic haemodialysis because evidence of a clear benefit is still lacking and severe side effects are feared. The aim of our retrospective study was to analyse the methods of dose adjustment and the clinical course of chronic haemodialysis patients with malignancies treated by chemotherapy. METHODS Between...

Tablet splitting is an accepted practice for the administration of drugs for a variety of reasons, including dose adjustment, ease of swallowing and cost savings. The purpose of this study was to evaluate the physical properties of lisinopril tablets as a result of splitting the tablets either by hand or with a splitting device. The impact of the splitting technique of lisinopril (Zestril® tabl...

In previous editions, this chapter was titled “Adaptation.” The literature uses the terms “adaptation” and “adjustment” interchangeably. Although either term could be used, this author prefers the term “adjustment,” as the term better describes a process as well as a final outcome. Adjustment refers to the changes in life that are made continuously when one has a chronic illness. Adjustment is ...