Gastric cancer with double metastasis to the orbit and duodenum is extremely rare. We report the case of a patient with gastric adenocarcinoma who presented with synchronous orbital and duodenal metastases at the time of initial diagnosis. A 60-year-old man presented with a 1-month history of visual disorder and pain in his right eye. He underwent ophthalmological examinations. The biopsy resul...

Pulmonary sarcomatoid carcinoma (PSC) is a rare histologic subtype of non-small cell lung cancer (NSCLC). The incidence ranges from 0.1% to 4.7% of all lung malignancies. However, Synchronous Intrahepatic cholangiocarcinoma (ICC) with primary pulmonary sarcomatiod carcinoma are much rarer double-cancer. Such a case has not previously been reported till now according to the literature. The coinc...

Primary localised amyloidosis of the urethra is a rare entity with only 50 cases reported in literature. The deposition fibrillary proteins can lead to range symptoms. Importantly, clinical and cystoscopic features may mimic urethral malignancy (haematuria, voiding difficulties, palpable mass), so thorough investigation required order exclude malignancy, identify generalised which has poor prog...

BACKGROUND Primary squamous cell carcinoma (SCC) of the thyroid gland is a rare malignancy that presents with advanced disease and poor prognosis. METHODS A 75-year-old woman with a history of Hashimoto thyroiditis presented with 6 months of dysphagia and stridor. Imaging revealed a thyroid mass invading the larynx. Primary SCC of the thyroid was diagnosed by histopathologic and immunohistoch...

INTRODUCTION The incidence of multiple primary cancers is reported to be between 0.3% and 4.3%. The second primary lesion is identified either simultaneously with the primary lesion (synchronous) or after a period of time (metachronous). Few cases of metastasis of breast carcinoma to the esophagus and vice versa have been reported in the past. CASE PRESENTATION We report an extremely rare cas...

background and objectives: gliomas are the most prevalent primary brain tumors. the purpose of this retrospective cohort study was evaluation of clinical trend and prognosis of patients with brain glioma and effective factors in prognosis. materials and methods: hundred and forty-five patients with supratentorial brain glioma, treated in shahid mostafa khomeini & hazrat-e-rasool hospitals i...

Abstract Hepatocellular carcinoma (HCC) is the commonest malignancy in Egypt secondary to endemic hepatitis virus. Dual with HCC infrequently reported. We herein retrospectively collected data of patients another primary tumor from a tertiary cancer center. Fifteen were enrolled this case series, epidemiologic data, type second malignancy, time interval between both tumors, treatment applied, a...

The objective of our two case reports is to increase awareness of the simultaneous occurrence of primary hyperparathyroidism and malignancy in patients that presents with hypercalcaemia. This report reviews the case reports from the history, investigation, treatment and outcome for these two patients. A literature review of the association between malignancy and primary hyperparathyroidism was ...