نتایج جستجو برای: dried blood spot test

تعداد نتایج: 1483626  

Journal: :Clinica chimica acta; international journal of clinical chemistry 2013
Ramakrishna S Sista Tong Wang Ning Wu Carrie Graham Allen Eckhardt Theodore Winger Vijay Srinivasan Deeksha Bali David S Millington Vamsee K Pamula

PURPOSE New therapies for lysosomal storage diseases (LSDs) have generated interest in screening newborns for these conditions. We present performance validation data on a digital microfluidic platform that performs multiplex enzymatic assays for Pompe, Fabry, Hunter, Gaucher, and Hurler diseases. METHODS We developed an investigational disposable digital microfluidic cartridge that uses a si...

2008
W Stevens G Sherman1 R Downing L.M Parsons C.-Y Ou S Crowley G.M Gershy-Damet K Fransen M Bulterys L Lu J Homsy T Finkbeiner J.N Nkengasong

A two day meeting hosted by the World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention (CDC) was held in May 2006 in Entebbe, Uganda to review the laboratory performance of virologic molecular methods, particularly the Roche Amplicor DNA PCR version 1.5 assay, in the diagnosis of HIV-1 infection in infants. The meeting was attended by approximately 60 participan...

Journal: :The Journal of the Association of Physicians of India 2007
Anjali F S Geethanjali R Selva Kumar M S Seshadri

BACKGROUND AND OBJECTIVES Glycated hemoglobin (HbA1c) provides an accurate and reliable method to assess the glycemic control in patients with Diabetes. Its measurement is limited by the inconvenience of sample collection that requires venipuncture, sample handling and storage factors. The aim of this study was to assess the feasibility of using a dried capillary blood spot on a filter paper to...

2013
Peter N. Fonjungo Mulu Girma Zenebe Melaku Teferi Mekonen Amilcar Tanuri Bereket Hailegiorgis Belete Tegbaru Yohannes Mengistu Aytenew Ashenafi Wubshet Mamo Tesfay Abreha Gudetta Tibesso Artur Ramos Gonfa Ayana Richard Freeman John N. Nkengasong Solomon Zewdu Yenew Kebede Almaz Abebe Thomas A. Kenyon Tsehaynesh Messele

BACKGROUND Early diagnosis of infants infected with HIV (EID) and early initiation of treatment significantly reduces the rate of disease progression and mortality. One of the challenges to identification of HIV-1-infected infants is availability and/or access to quality molecular laboratory facilities which perform molecular virologic assays suitable for accurate identification of the HIV stat...

Journal: :Papua and New Guinea medical journal 2012
B John T Lupiwa P Toliman E Lavu P Zimmerman P M Siba J Markby

Human immunodeficiency virus (HIV) is a significant public health issue in Papua New Guinea (PNG). After heterosexual transmission (90%), the second most common route of transmission is vertically from mother to child (3.5%). Before the introduction of molecular methods of HIV testing in PNG, diagnosing exposed infants was problematic because there were no reliable assays available for accurate...

2014
Ann M. Buchanan Dorothy E. Dow Charles G. Massambu Balthazar Nyombi Aisa Shayo Rahma Musoke Sheng Feng John A. Bartlett Coleen K. Cunningham Werner Schimana

BACKGROUND Mother to child transmission (MTCT) of HIV-1 remains an important problem in sub-Saharan Africa where most new pediatric HIV-1 infections occur. Early infant diagnosis of HIV-1 using dried blood spot (DBS) PCR among exposed infants provides an opportunity to assess current MTCT rates. METHODS We conducted a retrospective data analysis on mother-infant pairs from all PMTCT programs ...

Journal: :Archives of disease in childhood 1982
K Adriaenssens L Van Riel

Pancreatic lipase catalyses the hydrolysis of emulsified triglycerides to form a transparent solution of monoglycerides and fatty acids. Levels of serum pancreatic lipase were measured in neonates known to have cystic fibrosis and compared with levels in control infants. During the first weeks of life infants with cystic fibrosis had raised serum pancreatic lipase values in parallel with raised...

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