نتایج جستجو برای: drug combination

تعداد نتایج: 926095  

Journal: :Eurasian Journal of Veterinary Sciences 2020

Journal: :basic and clinical neuroscience 0
gholamreza kaka neuroscience research center, baqiyatallah university of medical science, tehran, iran. ramin rahmanzade neuroscience research center, shahid beheshti university of medical sciences, tehran, iran. farzin safee neuroscience research center, shahid beheshti university of medical sciences, tehran, iran. abbas haghparast neuroscience research center, shahid beheshti university of medical sciences, tehran, iran.

combined use of an opioid with a psychostimulant is popular among drug abusers. such “polydrug use” may increase drug effects or attenuate adverse effects of either drug alone. we proposed that a combination of methamphetamine (meth) and morphine may change physical opioid withdrawal symptoms. adult male rats were chronically injected with cumulative subcutaneous (s.c.) doses of morphine, meth ...

Journal: :Okayama Igakkai Zasshi (Journal of Okayama Medical Association) 2011

Journal: :Antimicrobial agents and chemotherapy 2006
David A Kocisko Byron Caughey John D Morrey Richard E Race

Combination treatment with pentosan polysulfate and Fe(III)meso-tetra(4-sulfonatophenyl)porphine in mice beginning 14 or 28 days after scrapie inoculation significantly increased survival times. This increase may be synergistic, implying that the compounds act cooperatively in vivo. Combination therapy may therefore be more effective for treatment of transmissible spongiform encephalopathies an...

Journal: :The Indian journal of medical research 2006
T K Jha

Pentavalent antimonials (SbV) have been successfully used for treatment of kala-azar since last six decades. Since 1970s its conventional dosages have failed to achieve with 60 per cent unresponsiveness reported with WHO regimen in Bihar (India). Pentamidine initially used as a second line of drug, acquired resistance (25%) even with prolonged dosage. Newer oral drug miltefosine is a potent ant...

Journal: :Biometrical journal. Biometrische Zeitschrift 2005
Roel Straetemans Timothy O'Brien Luc Wouters Jacky Van Dun Michel Janicot Luc Bijnens Tomasz Burzykowski Marc Aerts

In this paper we present and discuss a novel, simple and easy to implement parametric modeling approach to assess synergy. An extended three parameter log-logistic model is used to analyse the data and calculate confidence intervals of the interaction indices. In addition the model corrects for the bias due to plate-location effects. The analysis is performed with PROC NLMIXED and SAS-code is p...

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