AIM To analyze the clinical impact of preformed antiHLA-Cw vs antiHLA-A and/or -B donor-specific antibodies (DSA) in kidney transplantation. METHODS Retrospective study, comparing 12 patients transplanted with DSA exclusively antiHLA-Cw with 23 patients with preformed DSA antiHLA-A and/or B. RESULTS One year after transplantation there were no differences in terms of acute rejection between...

Bayesian Optimization (BO) is a data-efficient method for global black-box optimization of an expensive-to-evaluate fitness function. BO typically assumes that computation cost of BO is cheap, but experiments are time consuming or costly. In practice, this allows us to optimize ten or fewer critical parameters in up to 1,000 experiments. But experiments may be less expensive than BO methods ass...

Dynamic Spectrum Access (DSA) allows unlicensed wireless devices to opportunistically access unoccupied licensed spectrum bands. DSA yields efficient spectrum utilization which can greatly improve wireless networking performance. In this paper, we advocate application-awareness to effectively manage the sideeffects of DSA that can offset its benefits by adversely impacting application QoS. Simp...

BACKGROUND We evaluated the clinical relevance of pretransplant donor-specific HLA antibodies (DSA) in renal transplantation patients who had negative T-cell cytotoxicity crossmatches. METHODS From 328 consecutive renal transplant recipients, we selected 28 patients who had positive pretransplant (historical or at the time of transplantation) flow cytometry crossmatches, but negative T-cell c...

Rupture of an aneurysm is the major cause of subarachnoid hemorrhage (SAH). This condition has a mortality rate of 40-60%, and 10-20% of the survivors remain functionally dependent (1-3). Rapid diagnosis and an immediate treatment decision are of crucial importance because a delay in diagnosis increases the morbidity and mortality rate. Aneurysms may be treated by surgical clipping or endovascu...

In the CCD-based fine tracking optical system (FTOS), the whole disturbance suppression ability (DSA) is the product of the inner loop and outer position loop. Traditionally, high sampling fiber-optic gyroscopes (FOGs) are added to the platform to stabilize the line-of-sight (LOS). However, because of the FOGs' high cost and relatively big volume relative to the back narrow space of small rotat...

AIMS Three-dimensional reconstruction of intracranial vessels is of interest for evaluation of aneurysms. This study determined diagnostic difference of three-dimensional digital subtraction angiography (3D-DSA, volume-rendering image) versus 2D-DSA for evaluating ruptured intracranial aneurysms, particularly focusing on the size of aneurysms as depicted in both images. SETTINGS AND DESIGN Si...

BACKGROUND AND PURPOSE CTA is becoming the frontline modality to reveal aneurysms in patients with SAH. However, in about 20% of SAH patients no aneurysm is found. In these cases, intra-arterial DSA is still performed. Our aim was to evaluate whether negative findings on CTA can reliably exclude aneurysms in patients with acute SAH. MATERIALS AND METHODS We conducted a retrospective analysis ...

The electronic structure and charge transport property of 9,10-distyrylanthracene (DSA) and its derivatives with high solid-state luminescent efficiency were investigated by using density functional theory (DFT). The impact of substituents on the optimized structure, reorganization energy, ionization potential (IP) and electronic affinity (EA), frontier orbitals, crystal packing, transfer integ...

Cerebral vascular disease is responsible for nearly 800 000 hospital admissions annually with a total healthcare cost of $34 billion. Neuro-interventional surgery is at the forefront of fast-response assessment and intervention to assess patients’ health using digital subtraction angiography (DSA). Unfortunately, cerebral blood flow cannot be reliably measured with DSA during intervention. In t...