Purpose Descemet's stripping automated endothelial keratoplasty (DSAEK) is more difficult in hypotonic eyes with filtering bleb, due to the difficulties in elevating the intraocular pressure (IOP). We report a new method that uses ophthalmic viscoelastic devices (OVDs) to achieve good graft adhesion. Case Presentation We performed modified DSAEK surgery on 2 eyes of 2 patients, who had previo...

We report a case series of three patients with previous trabeculectomies who developed elevated intraocular pressure (IOP) in the immediate postoperative period after routine Descemet stripping automated endothelial keratoplasty (DSAEK). All patients had functioning trabeculectomies preoperatively, and developed elevated IOP between 41 and 69 mm Hg within 24 hours following DSAEK surgery. The I...

purpose: to compare corneal biomechanical properties and intraocular pressure (iop) in eyes with pseudophakic bullous keratopathy (pbk) before and after descemet stripping automated endothelial keratoplasty (dsaek). methods: this prospective non-randomizedintrasubject comparative study was conducted on 44eyes of 22 patients with the diagnosis ofpbk who underwent dsaek in one eye.intraocular pre...

PURPOSE To evaluate the use of a femtosecond laser combined with a microkeratome in the preparation of posterior corneal disks for Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS This experimental study involved ultrathin DSAEK tissue preparation of 22 donor corneas unsuitable for transplantation. The first cut was performed with an Intralase® FS60 laser and the second ...

PURPOSE To study the histopathological findings of the early cases of failed DSAEK grafts and to analyze the causes of graft failure. METHODS Retrospective study of 13 failed DSAEK grafts (four grafts submitted alone with no host cornea) of 12 patients. The histopathologic features are correlated with the clinical and operative findings. RESULTS Significant attenuation of the endothelial ce...

PURPOSE To evaluate myofibroblast differentiation as an etiology of haze at the graft-host interface in a cat model of Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK). METHODS DSAEK was performed on 10 eyes of 5 adult domestic short-hair cats. In vivo corneal imaging with slit lamp, confocal, and optical coherence tomography (OCT) were performed twice weekly. Cats were sacrifi...

PURPOSE To investigate the topographic characteristics of the posterior corneal surface after Descemet's endothelial membrane keratoplasty (DMEK) and Descemet's stripping automated endothelial keratoplasty (DSAEK) and their effects on postoperative visual acuity. METHODS Nineteen eyes of 19 patients after DMEK, 23 eyes of 23 patients after DSAEK, and 18 eyes of 18 control subjects were retros...

PURPOSE The aim of this study was to describe the aims, methods, donor and recipient cohort characteristics, and potential impact of the Cornea Preservation Time Study (CPTS). METHODS The CPTS is a randomized clinical trial conducted at 40 clinical sites (70 surgeons) designed to assess the effect of donor cornea preservation time (PT) on graft survival 3 years after Descemet stripping automa...

purpose: to investigate the biomechanical features of transplanted corneas after penetrating keratoplasty (pk), deep anterior lamellar keratoplasty (dalk), and descemet stripping automated endothelial keratoplasty (dsaek) and compare these measurements with those of a normal group. methods: forty-five eyes of 36 patients underwent pk, 23 eyes of 21 patients received dalk using anwar’s big bubbl...