To determine whether children who demonstrate dexamethasone suppression test (DST) nonsuppression have lower plasma dexamethasone levels than DST suppressors, we administered the DST to 73 patients ranging in age from 5-14 years. Plasma dexamethasone levels and postdexamethasone cortisol levels were measured at 4:00 PM on day 2. We found: (1) DST nonsuppressors had significantly lower plasma de...

OBJECTIVE A nationwide anti-tuberculosis drug resistance survey for Mycobacterium tuberculosis was conducted by the Tuberculosis Research Committee (Ryoken) in Japan, 2002, to clarify the recent trend of drug resistant M. tuberculosis. The drug susceptibility testing (DST) results by participating laboratories were compared with the test results by the reference laboratory, in order to evaluate...

Geomagnetic storms and substorms develop under strong control of the solar wind. This is demonstrated by the fact that the geomagnetic activity indices Dst and AE can be predicted from the solar wind alone. A consequence of the strong control by a common source is that substorm and storm indices tend to be highly correlated. However, a part of this correlation is likely to be an e€ect of intern...

Developmental systems theory (DST) is a general theoretical perspective on development, heredity and evolution. It is intended to facilitate the study of interactions between the many factors that influence development without reviving ‘dichotomous’ debates over nature or nurture, gene or environment, biology or culture. Several recent papers have addressed the relationship between DST and the ...

This study investigated the effect of applying the dynamic system theory (DST) and cognitive linguistics (CL) insights into grammar instruction on EFL learners’ learning of English prepositions and learner autonomy. Sixty Iranian EFL learners at the lower-intermediate level of language proficiency were randomly assigned to 1 experimental and 1 control group. The 2 groups filled out an autonomy ...

OBJECTIVE Diabetes or impaired glucose tolerance are common in patients with Cushing's syndrome (CS). In this study we investigated the incidence of subclinical Cushing's syndrome (SCS) in type 2 diabetic patients with poor and good metabolic control and the relationship between blood glucose and cortisol levels. DESIGN A total of 400 type 2 diabetes mellitus (T2DM) patients (Group A, HbA1c ≥...

UNLABELLED Rifampicin (R) and isoniazid (H) are key first-line anti-tuberculosis drugs. Failure to detect resistance to these two drugs early results in treatment failure and poor clinical outcomes. The study purpose was to validate the use of the GenoType MTBDRplus line probe assay (LPA) to detect resistance to R and H in Mycobacterium tuberculosis strains directly from smear-positive sputum s...

BACKGROUND Donor-specific blood transfusion (DST) prior to solid organ transplantation has been shown to induce long-term allograft survival in the absence of immunosuppressive therapy. Although the mechanisms underlying DST-induced allograft tolerance are not well defined, there is evidence to suggest DST induces one or more populations of antigen-specific regulatory cells that suppress allogr...

BACKGROUND Bills have been put forward in the UK and Republic of Ireland proposing a move to Central European Time (CET). Proponents argue that such a change will have benefits for road safety, with daylight being shifted from the morning, when collision risk is lower, to the evening, when risk is higher. Studies examining the impact of daylight saving time (DST) on road traffic collision risk ...

Tolerance to a vascularized allograft can be induced in adult animals by pregraft donor-specific blood transfusion (DST). Mechanisms underlying this effect appear to depend on unresponsiveness of alloreactive T-helper cells. In this study, we examined the roles of DST and cellular components of the allograft that are important in inducing T-cell unresponsiveness in a rat model. DST alone did no...