In Saccharomyces cerevisiae, transcriptionally silent heterochromatin at HML and HMR loci is established by silencers that recruit SIR complex and promote its propagation along chromatin. Silencers consist of various combinations of two or three binding sites for origin recognition complex (ORC), Abf1 and Rap1. A single ORC, Abf1 or Rap1 site cannot promote silencing, but can enhance silencing ...

Regasification systems in Floating Storage Units (FSRUs) that use the steam generated by boilers as heat source (closed loop) liquefied natural gas (LNG) regasification process are less detrimental to marine environment than those seawater (open loop). Their drawback, however, lies significant increase fuel consumption and, thus, CO2 emissions. The present paper performs an energy, exergy and e...

The origin recognition complex (ORC) is a conserved heterohexamer required for the formation of pre-replication (pre-RC) complexes at origins of DNA replication. Many studies of ORC subunits have been carried out in transformed human cell lines but the properties of ORC in primary cells have not been addressed. Here, we compare the expression levels and chromatin-association of ORC subunits in ...

Organic Rankine Cycle (ORC) is named for its use of an organic, high molecular mass fluid that boils at a lower temperature than the water. Among many well-proven technologies, the ORC is one of the most favorable and promising ways for low-temperature applications. In comparison to water, organic fluids are advantageous when the plant runs at low temperature or low power. The ORC is scalable t...

Organic Rankine Cycle (ORC) power systems are nowadays an option for local and domestic cogeneration of heat and electric power. Very interesting are micropower systems for heat recovery from low potential (40–90 °C) waste and renewable heat sources. Designing an ORC system dedicated to heat recovery from such a source is very difficult. Most important problems are connected with the selection ...

Web Services orchestrations require a firm mathematical basis for their development. We start from the Orc formalism proposed by J. Misra and co-workers, at Austin University. Orc is small and elegant and captures the essence of orchestrations. We translate Orc into colored Petri net systems, a generalization of Petri nets allowing to handle recursion—this formalism was recently proposed by Dev...

Turbo-expander is the most crucial and expensive component in Organic Rankine Cycle (ORC) power generation systems. The turbine engineering, design and research development process for ORC system is costly, time-consuming, and difficult for new-entrants in the ORC field. This paper investigates the re-design and retrofit of an off-the-shelf turbocharger for use in a 1 kW ORC system. The expande...

Open radical cystectomy (ORC) is the current gold standard treatment for muscle invasive bladder cancer. As surgeons become more proficient in minimally invasive and robotic surgical techniques, the number of patients undergoing robotic-assisted radical cystectomy (RARC) is increasing. Although minimally invasive methods are on the rise, research that critically compares open surgery with robot...