نتایج جستجو برای: dutasteride
تعداد نتایج: 380 فیلتر نتایج به سال:
PURPOSE Previous studies demonstrated a negative correlation between prostate volume and biopsy yield. By decreasing prostate volume 5alpha-reductase inhibitors may enhance cancer detection, which may explain the greater detection of high grade tumors in the finasteride arm of the Prostate Cancer Prevention Trial. MATERIALS AND METHODS A mathematical model was constructed to analyze the effec...
Therapeutic Class Overview/Summary: The agents approved for the treatment of signs and symptoms of benign prostatic hyperplasia (BPH) will be the focus of this review. The α-adrenergic blockers including, alfuzosin, doxazosin, silodosin, tamsulosin, and terazosin, reduce smooth-muscle tone in the prostate and bladder neck decreasing lower urinary tract symptoms (LUTS) secondary to BPH. Alfuzo...
PURPOSE Increasing evidence indicates that enhanced intratumoral androgen synthesis contributes to prostate cancer progression after androgen deprivation therapy. This phase II study was designed to assess responses to blocking multiple steps in androgen synthesis with inhibitors of CYP17A1 (ketoconazole) and type I and II 5alpha-reductases (dutasteride) in patients with castration-resistant pr...
Correspondence: Thomas H Tarter Division of Urology, Southern Illinois University School of Medicine, PO Box 19665, Springfield, IL 62794-9665, US. Tel +1 217 545 7390 Fax +1 217 545 7305 email [email protected] Abstract: Benign prostatic hyperplasia (BPH) is a frequent cause of lower urinary symptoms, with a prevalence of 50% by the sixth decade of life. Hyperplasia of stromal and epithelial ...
Introduction. Frontal fibrosing alopecia (FFA) is known as a lymphocytic primary cicatricial alopecia. The main characteristic of FFA progressive frontotemporal hairline recession. pathogenesis not completely understood. Destructing the stem cells epithelial hair follicles causes permanent loss and seems to be cause FFA. Studies have reported significantly decreased quality life in patients wit...
Special Announcement (Update 12/11/12): The American Society of Clinical Oncology (ASCO) and the American Urological Association (AUA) have archived this collaborative 2008 guideline on the Use of 5-alpha Reductase Inhibitors for Prostate Cancer Chemoprevention. The guideline has been removed from the main “Clinical Guidance” section of the www.AUAnet.org website, but is available in the “Archi...
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