Gastroesophageal reflux disease (GERD) is the main known etiological factor for Barrett's esophagus (BE), and BE is the precursor lesion of esophageal adenocarcinoma. The prevalence of BE is reported mostly from gastroenterology centers and there are only a few reported cases from outpatients with dyspepsia. A large number of patients with GERD have degrees of dyspepsia. This study primarily ai...

Aim: To determine the prevalence of H. pylori and associated upper gastrointestinal lesions among dyspeptic patients seen at a tertiary health centre in northern Nigeria.Methods: One hundred and ninety two (192) dyspeptic patients undergoing upper gastrointestinal endoscopy at the Federal Medical Centre Gombe were retrospectively studied. Gastric mucosal biopsy specimens were stained with haema...

INTRODUCTION Helicobacter pylori is a gram-negative urease-producing bacterium causally linked with gastritis, peptic ulcer disease and gastric adenocarcinoma. Infection is more frequent and acquired at an earlier age in developing countries compared to European populations. The incidence of Helicobacter pylori infection in dyspeptic Ghanaian patients was 75.4%. However, epidemiological factors...

Helicobacter pylori (HP) chronic gastritis can lead to precursor stages of gastric cancer. New biological markers have been proposed to study the gastric mucosal state. We evaluate biological results in comparison with histological ones in a dyspeptic population. Forty nine dyspeptic patients underwent endoscopy with gastric biopsies for histological examination. Blood samples were obtained to ...

Gastroesophageal reflux disease (GERD) is the main known etiological factor for Barrett’s esophagus (BE), and BE is the precursor lesion of esophageal adenocarcinoma. The prevalence of BE is reported mostly from gastroenterology centers and there are only a few reported cases from outpatients with dyspepsia. A large number of patients with GERD have degrees of dyspepsia. This study primarily ai...

Functional dyspepsia is a clinical syndrome defined by chronic or recurrent symptoms of pain or discomfort centred upon the upper abdomen without a cause being identified by conventional diagnostic means. 1 The pathophysi-ology of functional dyspepsia is unknown but a number of mechanisms have been proposed, such as delayed gastric emptying, hypersensitivity to gastric distension, impaired acco...

Helicobacter pylori infection is one of the most frequent causes of dyspepsia in the general population. As gastrointestinal symptoms are a common complaint among HIV-positive persons, the purpose of the present study is to assess the role of Helicobacter pylori infection in this category of patients. We performed a retrospective, case-control study on two groups of HIV-infected patients admitt...

OBJECTIVE We aimed at investigating the relationship between Helicobacter pylori infection and in vivo lipid peroxidation and platelet activation, as reflected by urinary 8-iso-prostaglandin (PG)F(2alpha) and 11-dehydro-thromboxane (TX)B2, respectively, in otherwise healthy dyspeptic subjects. METHODS AND RESULTS We measured urinary 8-iso-PGF2alpha and 11-dehydro-TXB2 excretion in 40 dyspepti...

BACKGROUND Non-ulcer dyspepsia is predominantly a self-managed condition, although it accounts for a significant number of general practitioner consultations and hospital referrals. Herbal medicinal products are often used for the relief of dyspeptic symptoms. AIMS : To critically assess the evidence for and against herbal medicinal products for the treatment of non-ulcer dyspepsia. METHODS...

OBJECTIVE To compare the effects of drinking white wine or black tea with Swiss cheese fondue followed by a shot of cherry schnapps on gastric emptying, appetite, and abdominal symptoms. DESIGN Randomised controlled crossover study. PARTICIPANTS 20 healthy adults (14 men) aged 23-58. INTERVENTIONS Cheese fondue (3260 kJ, 32% fat) labelled with 150 mg sodium (13)Carbon-octanoate was consum...