Atria from dystrophic and non-dystrophic mice were examined by light and electron microscopy. Particular attention was paid to the granularity of the specific atrial granules and the development of the Golgi apparatus. At the light microscopic level, both a decrease in number and degenerative changes were recognized in the atrial cardiocytes, which were intercalated by increased connective and ...

Duchenne muscular dystrophy (DMD) is a disease of progressive destruction of striated muscle, resulting in muscle weakness with progressive respiratory and cardiac failure. Respiratory and cardiac disease are the leading causes of death in DMD patients. Previous studies have suggested an important link between cardiac dysfunction and hypoxia in the dystrophic heart; these studies aim to underst...

1. The dose of pentobarbitone required for anaesthesia was significantly greater for dystrophic hamsters than for normal animals. 2. Serum creatine kinase activity was significantly higher in dystrophic than in normal hamsters. 3. Brain, heart and tibialis anterior muscle from dystrophic animals contained significantly less creatine kinase than the normal tissues. 4. Creatine kinase in normal a...

Trachyonychia is a disorder of the nail unit that most commonly presents with rough, longitudinally ridged nails (opaque trachyonychia) or less frequently, uniform, opalescent nails with pits (shiny trachyonychia). The term trachyonychia refers to 'rough nails.' This article comprehensively reviews the clinical, histologic, and therapeutic aspects of trachyonychia. The authors' preferred evalua...

Abstract Epidermolysis bullosa simplex (EBS) is a heterogeneous, congenital, mucocutaneous fragility syndrome, characterized ultrastructurally by cleavage within the basal keratinocyte. Seventy-five per cent of cases are attributable to mutations in KRT5 and KRT14, vast majority which dominant negative mutations, resulting impaired keratin intermediate filament dynamics layer epidermis. The pre...

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Scapulothoracic fusion (STF) for painful winging of the scapula in neuromuscular disorders can provide effective pain relief and functional improvement, but there is little information comparing outcomes between patients with dystrophic and non-dystrophic conditions. We performed a retrospective review of 42 STFs in 34 patients with dystrophic and non-dystrophic conditions using a mul...

In order to study the problem of surface fluctuations and slag entrapment, the nail board experiment and simulation computation method was used to optimize the method for measuring liquid level characteristics in mold. The influence of steel nails diameter and the distance between steel nails on the measurement results was studied. The height of the liquid surface and the surface velocity at di...

We describe how isospin splitting and techniquark-technilepton splitting in one-family technicolor models can reduce the predicted value of the electroweak radiative correction parameter S, without making a large contribution to the T parameter.