We isolated and characterized the eagle gene, encoding a member of the steroid receptor superfamily in Drosophila. In the central nervous system eagle RNA was expressed in a limited number of cells. During stages 10 and 11, eagle RNA expression was observed in four neuroblasts, NB2-4, NB3-3, NB6-4 and NB7-3. Except for NB6-4, eagle RNA expression reached a maximum at the very beginning of expre...

Alport syndrome is a rare genetic disease and the second most common inherited cause of kidney failure, prevalent in about 60,000 persons United States 103,000 European Union. The present study to evaluate longer-term safety tolerability bardoxolone methyl (Bard) an open-label extended access (EAGLE; NCT03749447) for patients who completed prior qualifying clinical trial with (CARDINAL; NCT0301...

Eagle's syndrome or styalgia is characterised by the anatomical bone deformity of styloid process, as identified Wat W. Eagle in 19491. An aggregate symptoms caused elongation and severe calcification temporal bone's well ligaments attached to this including stylomandibular ligaments, have been identified2. The process typically 20 30 mm length, patients with elongated processes 40 longer clini...

BACKGROUND AND AIM: This study was performed to evaluate and compare the calcification patterns of the stylohyoid ligament in Eagle’s syndrome (ES) patients, and asymptomatic patients with elongated styloid process (SP) via cone-beam computed tomography (CBCT).METHODS: A total of 52 CBCT images in two symptomatic (ES) and asymptomatic groups (n = 26 per group) were assessed. The mean length an...