From an ext,ensive series of experiments with whole embryos and with tissue mince, Needham and his coworkers (l-7) concluded that in the early chick embryo the phosphorylation route of glycolysis, the Meyerhof-Embden cycle, is imperfectly established. Because glycogen generally failed to be converted to lactic acid, they argued that the enzyme esterifying glycogen was absent or insufficient. Si...