The preparations and characterization of polypyrrole – polyethylene glycol (PPy-PEG) films are reported in this paper. The composite films were synthesized by electrochemical method in 0.2 mol·L-1 Py and 5% PEG in 0.2 mol·L-1 oxalic acid. The electrochemical behaviour of PPy and PPy-PEG coatings has been investigated in phosphate buffer solution (PBS) by cyclic voltammetry, Tafel plots and elec...

Electrochemical Impedance Spectroscopy (EIS) is frequently used for the study of electrochemical reactions and associated mechanisms phenomena. To a specific reaction, it important to choose DC potential at which measured impedance data carries information mostly related that reaction. One first questions asked was: different potentials, reaction contributes most recorded spectra, cathodic or a...

We report on the aptadetection of chloramphenicol (CAP) using electrochemical impedance spectroscopy. The detection principle is based on the changes of the interfacial properties of the electrode after the interaction of the ssDNA aptamers with the target molecules. The electrode surface is partially blocked due to the formation of the aptamer-CAP complex, resulting in an increase of the inter...

Highly aligned multi-wall carbon nanotubes were synthesized in the shape of towers and embedded into fluidic channels as electrodes for impedance measurement of LNCaP human prostate cancer cells. Tower electrodes up to 8 mm high were grown and easily peeled off a silicon substrate. The nanotube electrodes were then successfully soldered onto patterned printed circuit boards and cast into epoxy ...

The electrochemical impedance of an iron electrode often shows the capacitive and inductive loops on the complex plane. The capacitive loop originates from the time constant of the charge transfer resistance and the electric double layer capacitance. The inductive loop is explained by Faradaic processes involving the reaction intermediate. In some cases, these loops deviate from a true semicirc...

Here, we report development of the galvanostatic Fourier transform electrochemical impedance spectroscopy (FTEIS), which monitors impedance of electrochemical reactions activated by current steps. We first derive relevant relations for potential change upon application of a step current, obtain impedances theoretically from the relations by simulation, and verify them with experimental results....

Molybdenum electrode based flexible biosensor on porous polyamide substrates has been fabricated and tested for its functionality as a protein affinity based biosensor. The biosensor performance was evaluated using a key cardiac biomarker; cardiac Troponin-I (cTnI). Molybdenum is a transition metal and demonstrates electrochemical behavior upon interaction with an electrolyte. We have leveraged...

Electrochemical analysis allows in situ characterization of solid oxide electrochemical cells (SOCs) under operating conditions. However, the SOCs that have been analyzed in this way have ill-defined or uncommon microstructures in terms of porosity and tortuosity. Therefore, the nano-scale characterization of SOCs with respect to three-phase boundaries has been hindered. We introduce novel in s...

While oligonucleotide hybridization and effects of nucleobase mismatches have been the intense focus of a number of electrochemical studies, the effects of the target strand length on the electrochemical response of oligonucleotide films have not been addressed yet. In this report, we have studied the electrochemical impedance of the oligonucleotide films having overhangs on either the target o...