PURPOSE To determine the stimulus conditions required to elicit rod-driven, focal macular electroretinograms (rod FMERGs). METHODS A blue (lambda(max)=470 nm) stimulus, 5 degrees in size, was imaged at a luminance of 1.5 cd/m(2) on different regions of the human retina. Electroretinograms (ERGs) elicited by this stimulus were recorded from the light- and dark-adapted retina of four subjects w...

Focal electroretinograms (ERGs) from the green and red cone systems in combination were elicited with a method of rod silent substitution from three young patients with dominant retinitis pigmentosa with reduced penetrance. With this method, two alternating lights of different wavelength, matched in brightness for the rods, were presented to the same retinal area. The brighter light for the gre...

Full-field electroretinograms (ERGs) were recorded from three adult English setters with advanced neuronal ceroid lipofuscinosis and three normal controls. Affected setters showed 30% to 40% reductions in a-wave and b-wave amplitudes, normal cone and rod b-wave implicit times, and slightly elevated a-wave and b-wave thresholds. The ERGs of these affected setters differed from those that have be...

PURPOSE To assess the impact of blue-light filtering on retinal processing to evaluate potential side effects of these filters on visual function at the neural level. SETTING Department of Ophthalmology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany. DESIGN Cohort study. METHODS Multifocal electroretinograms (ERGs) were recorded monocularly after pupil dilation in pseudophaki...