Effect of nonsolvent in the polymer (polyvinyl butyral) solution in ethanol on the electrospinning performance and nanofiber properties was investigated. Water as the nonsolvent was added in various amounts to the polymer solution. Addition of water did influence neither surface tension nor conductivity of polymer solution significantly. On the other hand, it increased its viscosity. The perfor...

objective(s):the aim of this study was to prepare electrospun nanofibers of celecoxib using combination of time-dependent polymers with pectin to achieve a colon-specific drug delivery system for celecoxib. materials and methods:formulations were produced based on two multilevel 22 full factorial designs. the independent variables were the ratio of drug:time-dependent polymer (x1) and the amoun...

Hexagonal patterns of gold nanorods were made by assembling gold nanorod-coated poly(N-isopropyl acrylamide) microgels. The required population of nanorods on the microgels was achieved by attaching nanoparticle seeds on the latter and growing them to nanorods. The various materials prepared were characterized by UV-vis spectroscopy and transmission electron microscopy. Similar experiments with...

BACKGROUND Electrospinning is a non-mechanical processing strategy that can be used to process a variety of native and synthetic polymers into highly porous materials composed of nano-scale to micron-scale diameter fibers. By nature, electrospun materials exhibit an extensive surface area and highly interconnected pore spaces. In this study we adopted a biological engineering approach to ask ho...

Although electrospinning is considered a powerful and generic tool for the preparation of nanofiber webs, several issues still need to be overcome for real-world applications. Most of these issues stem from the use of a syringe-based system, where the key factor influencing successful electrospinning is the maintenance of several subtle balances such as those of between the mass and the electri...

Monodisperse alginate microgels (10-50 μm) are created via droplet-based microfluidics by a novel crosslinking procedure. Ionic crosslinking of alginate is induced by release of chelated calcium ions. The process separates droplet formation and gelation reaction enabling excellent control over size and homogeneity under mild reaction conditions. Living mesenchymal stem cells are encapsulated an...

Ellipsoid-shaped nanoclusters composed of single superparamagnetic nanoparticles can be generated by emulsion electrospinning. Stretching and subsequent solvent evaporation of iron oxide loaded emulsion droplets during the emulsion electrospinning process enables the creation of such structures embedded in polymer nanofibers. Dissolution of the polymer fibers yields an aqueous dispersion of the...

Electrospun nanofibers have gathered more consideration in worldwide to deliver the bioactive agents in a sustained manner for biomedical applications. In this study, chlorogenic acid loaded polycaprolactone nanofibers were fabricated by electrospinning process and the average fiber diameters were analyzed using scanning electron microscopy analysis. Further, Fourier transform infrared spectros...

The focus of this work is on composite materials of inorganic nanoparticles such as TiO2 embedded within microspheres of a responsive polymeric network. Microgels of N-isopropylacrylamide (NIPAM) with interpenetrating (IP) linear chains of poly(acrylic acid) (PAAc) were synthesized to promote the incorporation of TiO2. Dynamic light scattering measurements of the IP-microgels in aqueous environ...

Electrospun fibers are promising tissue engineering scaffolds that offer the cells an environment that mimics the native extracellular matrix. Fibers with different characteristics can be produced by the electrospinning technique according to the needs of the tissue to be repaired. In this review, the process of electrospinning was examined, providing a description of the common techniques used...