compounds were /V-acetylcysteine, bismuththiol. calcium glucarate, (±) catechin, diallyl disulfide, glycaric acid, i>-glucaro-l,4-lactone. \-(4hydro\yphenyl)retinamide, n-limonene, mesna, retinole acid, rutin, quercetin, silymarin, and taurine. In examining the nature of compounds that inhibited rat trachea! epithelial cell transformation, several possible chemoprevcntivc mechanisms appeared t...

The aim of the present study was to investigate the effect of ellagic acid on haloperidol-induced orofacial dyskinesia and catalepsy in Wistar male albino rats and to explore the possible underlying mechanisms for these effects. Haloperidol (1 mg/kg, ip) was administered on 21 successive days to induce orofacial dyskinesia in rats. Ellagic acid (10, 20 and 40 mg/kg, po) was administered for 21 ...

Recent studies have examined and demonstrated the potential cancer chemopreventive activity of freeze-dried berries including strawberries and black raspberries. Although ellagic acid, an abundant component in these berries, has been shown to inhibit carcinogenesis both in vivo and in vitro, several studies have reported that other compounds in the berries may also contribute to the observed in...

Ellagic acid has been demonstrated to inhibit the growth of several types of cancer cells. However, whether it sensitizes human colorectal carcinoma cells to 5-fluorouracil, has not yet been investigated. Colorectal carcinoma HT-29, Colo 320DM, SW480 and LoVo cells were treated with ellagic acid (2.5-25 μg/ml) and 5-fluorouracil (5-25 μM) alone and in combination and then the viability was asse...

The present paper deals with the structure, occurrence and biological activity of ellagitannins. Ellagitannins belong to the class of hydrolysable tannins, they are esters of hexahydroxydiphenoic acid and monosaccharide (most commonly glucose). Ellagitannins are slowly hydrolysed in the digestive tract, releasing the ellagic acid molecule. Their chemical structure determines physical and chemic...

The purpose of this thesis was to identify and quantify the non-anthocyanin phenolic compounds in Finnish berries. The compounds of interest were kaempferol, quercetin and myricetin (flavonols); p-coumaric, caffeic and ferulic acids (hydroxycinnamic acids); p-hydroxybenzoic, gallic and ellagic acids (hydroxybenzoic acids). These compounds were selected because of their proposed healthpromoting ...

This study aimed to assess the potential anti-angiogenic mechanism of Phyllanthus urinaria (P. urinaria) and characterize the major compound in P. urinaria that exerts anti-angiogenic effect. The water extract of P. urinaria and Ellagic Acid were used to evaluate the anti-angiogenic effect in chorioallantoic membrane (CAM) in chicken embryo and human vascular endothelial cells (HUVECs). The ma...

The bark of Terminalia arjuna is known for its heart-health benefits in ayurvedic literature. This has been further supported by in vivo studies on animal and human volunteers. But there is no detailed study on identification of the active ingredients such as polyphenols. Polyphenols possesses antioxidant properties and are well-known health actives, it is important to characterise polyphenols ...

The aim of the present study was to evaluate effect of ellagic acid, a polyphenol bioactive compound, on reserpine-induced orofacial dyskinesia in Wistar male albino rats and to explore the possible underlying mechanisms for this effect. Reserpine (1 mg kgG1, i.p.) was administered on every alternate day for a period of 5 days (day 1, 3 and 5) to induce orofacial dyskinesia in rats. Ellagic aci...

Background and Aims: During ageing in oak barrels, wine undergoes changes because of the release of polyphenols and other molecules from wood. The aim of this study was to evaluate the influence of some oak wood-derived volatile compounds, ellagic acid and oak wood extracts on the levels of (+)-catechin, procyanidin B1 and malvidin-3-glucoside. Methods and Results: Phenolics and the oak wood de...