نتایج جستجو برای: embryoid bodies

تعداد نتایج: 84874  

Journal: :Journal of cell science 1997
C Dani A G Smith S Dessolin P Leroy L Staccini P Villageois C Darimont G Ailhaud

Embryonic stem cells, derived from the inner cell mass of murine blastocysts, can be maintained in a totipotent state in vitro. In appropriate conditions embryonic stem cells have been shown to differentiate in vitro into various derivatives of all three primary germ layers. We describe in this paper conditions to induce differentiation of embryonic stem cells reliably and at high efficiency in...

Journal: :Journal of embryology and experimental morphology 1980
R H Lovell-Badge M J Evans

Two-dimensional electrophoresis was used to find changes in protein synthesis occurring as pluripotent embryonal carcinoma (EC) cells differentiate to give embryoid bodies in vitro. 2-D patterns from other embryonic cell lines, and from the inner cell mass (ICM) cells of mouse embryos, were also analysed for the expression of those proteins showing some change during embryoid body formation and...

Journal: :Blood 2006
Ruediger Liersch Filip Nay Lingge Lu Michael Detmar

The molecular mechanisms that regulate the formation of the lymphatic vascular system remain poorly characterized. Whereas studies in embryonic stem (ES) cells have provided major new insights into the mechanisms of blood vessel formation, the development of lymphatic endothelium has not been previously observed. We established embryoid bodies (EBs) from murine ES cells in the presence or absen...

2010
Zhongmin Zou Pauline A. Ocaya Huiqin Sun Frank Kuhnert Heidi Stuhlmann

Objective—Vezf1 encodes an early zinc finger transcription factor that is essential for normal vascular development and functions in a dose-dependent manner. Here, we investigated the role of Vezf1 during processes of endothelial cell differentiation and maturation by studying mutant Vezf1 embryonic stem (ES) cells using the in vitro embryoid body differentiation model and the in vivo teratocar...

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