one of the main important and challenging issues in substance use disorders is the comorbidity of diseases. in fact, substance use disorder falls into a special circumstance that is unlike any other disease in medical science. substance abuse patients typically and on purpose use illegal drugs (poison) in aim of damaging their nervous system and change function of their brains by applying subst...

BACKGROUND It has been proposed that gains would be made in the validity of the psychiatric classification system if many of the present 'neurotic' or personality disorders were subsumed into two over-arching groups, externalising and emotional disorders. If diagnostic sub-categories from the first digit coding structures within ICD-10 do, in fact, share clinical phenomenology that align with t...

OBJECTIVE Mental health conditions are associated with a significant burden on individuals. Using data from a large population health survey, the present study aimed to quantify the burden of emotional disorders (depression and anxiety) on health-related quality of life (HRQoL) in the region of Catalonia (Spain) for evidence-informed policy making. METHODS Regression models were used to estim...