Purpose: To formulate solid lipid microparticles (SLM) of loratadine (LRT) for the treatment of allergic reactions via the nasal route. Methods: Microparticles were prepared by emulsion congealing technique. The drug content of microparticles was analysed. Drug/excipient compatibility and crystallinity characteristics of microparticles were investigated by Fourier Transform Infrared Spectroscop...

Insulin-loaded PEG2-PLA40 and PEG5-PLA20 microspheres containing 5% bovine insulin were manufactured using single emulsion and w/o/w multiple emulsion-solvent evaporation techniques. Microspheres were characterized for their insulin encapsulation efficiency and release characteristics in phosphate-buffered saline (PBS) at pH 7.4 and 37 ÂC. Moreover, the stability of the peptide during 18 days o...

In drug therapy, most therapeutic drugs are of low molecular weight and could freely diffuse in the biological milieu depending on the administration route applied. The main reason for the development of polymeric drug carriers is to obtain desired effects such as sustained therapy, local and controlled release, prolonged activity and reduction of side effects. Alternatively, polymeric carriers...

Thanks to their outstanding advantages, nanostructured lipid carriers (NLCs) have recognized in various fields these days. One way to discover extra useful products against typical bacteria (e.g., Staphylococcus epidermidis) is NLCs loaded with essential oils. This paper aims to provide NLCs to encapsulate MA oil and characterize and survey the obtained MA...

ber af problems fer nnr instantaneously While solvent-assisted emulsion systems have met with a degree of success in formulating pressure sensitive adhesives, they have several disadvantages. The solvent content of these systems precludes totally solvent-free adhesives. Also. there is reported evidence that surfactants used to stabilize the emulsion can adversely affect tack properties of the f...

To elucidate the relationship between physicochemical properties, spray characteristics, and combustion performance, a series of experiments have been conducted in a constant volume vessel with injection of hydrous ethanol diesel emulsion and regular diesel. HE30 (emulsion with 30% volume fraction of 20% water-containing ethanol and 70% volume fraction of 0# diesel) is developed using Shah’s te...

The effect of silicone nano-emulsion softener against silicone conventional emulsion softener on the physical properties of cotton fabric has been studied. It is observed that the nano-emulsion softener improves the feel, softness and crease recovery to a higher extent compared to the conventional emulsion softener. However, the nano form of emulsion causes higher loss in strength with increase...