A broad consensus has not been reached on the appropriate timing for cessation of peritoneal dialysis (PD). Decreasing urine volume, repeated and refractory peritonitis, and deterioration of the peritoneal membrane are major reasons to stop PD. Also, the link between length of time on PD and encapsulating peritoneal sclerosis (EPS) should be an additional concern. The aim of the present study w...

Studies on infection-induced inflammatory reactions in humans rely largely on findings in the blood compartment. Peritoneal leukocytes from patients treated with peritoneal dialysis offer a unique opportunity to study in humans the inflammatory responses taking place at the site of infection. Compared with peritoneal macrophages (pMϕ) from uninfected patients, pMϕ from infected patients display...

Encapsulating peritoneal sclerosis (EPS) is a rare complication of dialysis which mortality can reach 50%. The usual treatment involves suspension the technique, medical treatment, and surgical enterolysis. We report case 36-year-old female who undergone continuous ambulatory without complications for 10 years. She presented at emergency department with abdominal pain diagnosis peritonitis was ...

Encapsulating peritoneal sclerosis (EPS) is a serious problem for chronically dialysed patients [1,2]. With an overall prevalence of 2–3% in patients undergoing peritoneal dialysis (PD), it is now obvious that extended duration of PD therapy increases the incidence and severity of EPS [3]. Mortality rates in patients with EPS remain high—especially after bowel obstruction becomes an overt probl...

AIM Encapsulating peritoneal sclerosis (EPS) is arguably the most serious complication of chronic peritoneal dialysis (PD) therapy with extremely high mortality rates. We aimed to establish the rates of EPS and factors associated with its development in a single center. METHODS We retrospectively reviewed the records of all our PD patients from 1 January 1989 until 31 December 2008. All suspe...

BACKGROUND Encapsulating peritoneal sclerosis (EPS) is a severe complication of peritoneal dialysis (PD). Previously, it has been shown that infiltrating CD4-positive T cells and M2 macrophages are associated with several fibrotic conditions. Therefore, the characteristics of the peritoneal cell infiltrate in EPS may be of interest to understand EPS pathogenesis. In this study, we aim to elucid...

We evaluated the usefulness of periodic abdominal irrigation through the peritoneal catheter preserved after termination of peritoneal dialysis (PD) to prevent encapsulating peritoneal sclerosis (EPS). The study group included 8 ̊patients in whom PD had been terminated (mean age: 53.1 ±̊ 7.1 ̊years; mean PD duration: 119.6 ±̊ 37.8 ̊months). The abdominal cavity was periodically irrigated through the...

Since 1993, we have performed enterolysis for encapsulating peritoneal sclerosis (EPS) in 86 patients. Five patients died after surgery, but the remaining 81 patients achieved symptomatic improvement. However, some of the surviving patients developed symptoms of intestinal obstruction after several months, and EPS recurrence remains our greatest challenge. In the present study, we identified fa...

BACKGROUND Encapsulating peritoneal sclerosis (EPS) is a serious complication of peritoneal dialysis (PD) with an increasing incidence. There is no clear consensus on the treatment of EPS, but anecdotal reports indicate improvement in EPS patients treated with tamoxifen. At present, there is no evidence for the effect of tamoxifen treatment in EPS patients. This study investigates the effect of...