نتایج جستجو برای: end resection
تعداد نتایج: 471996 فیلتر نتایج به سال:
Cryptogenic Multifocal Ulcerous Stenosing Enteritis (CMUSE) is a rare idiopathic disease of the small bowel. Its origin and pathophysiology has not been well described. Clinicopathologic features include unexplained ileal strictures with supercial ulceration. We present a case of a 31-year-old HIV positive lady who was admitted with complaints of recurrent abdominal pain and constipation. Labo...
Meets DNA Transcription and Recombination: When RNA Andrés Aguilera and Hélène Gaillard Mechanism and Regulation End Resection at Double-Strand Breaks: Lorraine S. Symington Resection in Homologous Recombination Structural Studies of DNA End Detection and Christian Linke-Winnebeck, et al. Christian Bernd Schiller, Florian Ulrich Seifert, The Dissolution of Double Holliday Junctions Anna H. Biza...
The RecQ helicase RECQL4, mutated in Rothmund-Thomson syndrome, regulates genome stability, aging, and cancer. Here, we identify a crucial role for RECQL4 in DNA end resection, which is the initial and an essential step of homologous recombination (HR)-dependent DNA double-strand break repair (DSBR). Depletion of RECQL4 severely reduces HR-mediated repair and 5' end resection in vivo. RECQL4 ph...
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