Cell has celebrated the powers of reductionist molecular biology and its major successes for four decades. Those who have participated in cancer research during this period have witnessed wild fluctuations from times where endless inexplicable phenomenology reigned supreme to periods of reductionist triumphalism and, in recent years, to a move back to confronting the endless complexity of this ...

This article examines how chikungunya virus disease is epidemiologically and politically invisible in Brazil, unlike other diseases related to the Aedes Aegypti mosquito, such as Zika, dengue, yellow fever. It demonstrates intricacy of identifying presence chikungunya, its effects are generally materialised pain, which difficult measure quantify, thus medical state bureaucracy. As with chronic ...

Following infection, the physical state of linear herpes simplex virus (HSV) genomes may change into an "endless" or circular form. In this study, using Southern blot analysis of the HSV genome, we provide evidence that immediate-early protein ICP4 is involved in the process of converting the linear HSV-1 ICP4-deleted mutant strain d120 genome into its endless form. Under conditions where de no...

We present a novel and uniform technique for normal logic program declarative error diagnosis. We lay down the foundations on a general approach to diagnosis using logic programming, and bring out the close relationship between debugging and fault{{nding. Diagnostic debugging can be enacted by contradiction removal methods. It relies on a simple program transformation to provide a contradiction...