I read with great interest the recent paper entitled " Con-vective washout reduces antidiarrheal efficacy of entero-cyte surface–targeted antisecretory drugs " by Jin et al. (2013) in the February 2013 issue of the Journal. In this paper, the influence on drug diffusion of adverse fluid convection was modeled by solving a diffusion convec-tion equation with appropriate boundary conditions. In e...

Owing to the rarity and biological clinical heterogeneity of gastroenteropancreatic neuroendocrine neoplasia (GEP NEN), management these patients may be challenging for physicians. This review highlights specific features GEP NEN with particular attention on role Ki67 heterogeneity, potential prognostic novel radiological techniques, usefulness functional imaging, including 68Ga-DOTA-SST PET/CT...

We designed a multiplex PCR for the detection of all categories of diarrheagenic Escherichia coli. This method proved to be specific and rapid in detecting virulence genes from Shiga toxin-producing (stx(1), stx(2), and eae), enteropathogenic (eae and bfp), enterotoxigenic (st II and lt), enteroinvasive (vir F and ipa H), entero-aggregative (aaf II), and diffuse adherent (daa E) Escherichia col...